Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDR1 | Q08345 | 12/20 | 0.47 |
| ▸ | DDR2 | Q16832 | 8/20 | 0.47 |
| ▸ | KIT | P10721 | 7/20 | 0.47 |
| ▸ | ABL1 | P00519 | 6/20 | 0.47 |
| ▸ | BCR | P11274 | 6/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | TTK | P33981 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 2/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | MC4R | P32245 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467002 | 0.91 | LMNA (0.54) | DDR1DDR2KITABL1BCR | |
| SCHEMBL3465798 | 0.80 | BRAF (0.51) | DDR1DDR2KITABL1BCR | |
| SCHEMBL3466290 | 0.80 | KIT (0.46) | DDR1DDR2KITABL1BCR | |
| SCHEMBL3466032 | 0.80 | RAD52 (0.49) | DDR1DDR2KITABL1BCR | |
| SCHEMBL3469410 | 0.79 | RAD52 (0.62) | BRAFFYN | |
| SCHEMBL3469213 | 0.77 | FYN (0.55) | DDR1DDR2KITABL1BCR | |
| SCHEMBL3466131 | 0.77 | RAD52 (0.46) | DDR1DDR2KITABL1BCR | |
| SCHEMBL3466661 | 0.75 | BRAF (0.52) | DDR1DDR2KITABL1BCR | |
| SCHEMBL3466303 | 0.75 | GAA (0.53) | DDR1DDR2KITABL1BCR | |
| SCHEMBL3466278 | 0.74 | FYN (0.47) | DDR1DDR2KITABL1BCR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |