Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 4/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | KDM1A | O60341 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.39 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.39 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467670 | 0.91 | AADAT (0.65) | AADATMEN1KMT2ALMNAALOX12 | |
| SCHEMBL3467541 | 0.89 | AADAT (0.56) | AADATMEN1KMT2ACA1CA2 | |
| SCHEMBL3467310 | 0.82 | MEN1 (0.43) | AADATMEN1KMT2ALMNAALOX12 | |
| SCHEMBL3467885 | 0.74 | ALDH1A1 (0.65) | MEN1KMT2ALMNAALOX12HTT | |
| SCHEMBL3468523 | 0.72 | ALDH1A1 (0.52) | MEN1KMT2ALMNAALOX12HTT | |
| SCHEMBL5388834 | 0.72 | KMT2A (0.59) | MEN1KMT2ALMNAALOX12HTT | |
| SCHEMBL3466833 | 0.71 | ALDH1A1 (0.54) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL3467663 | 0.71 | CA1 (0.74) | MEN1KMT2ALMNAALOX12HTT | |
| SCHEMBL9796293 | 0.71 | CA1 (0.81) | CA1CA2CA9 | |
| SCHEMBL5389518 | 0.70 | MEN1 (0.74) | MEN1KMT2ALMNAALOX12HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |