Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.74 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ABL1 | P00519 | 4/20 | 0.48 |
| ▸ | SRC | P12931 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467362 | 0.81 | CA1 (0.54) | CA1HTTALDH1A1 | |
| SCHEMBL3467885 | 0.81 | ALDH1A1 (0.65) | CA1MEN1MAPTKMT2ALMNA | |
| SCHEMBL3467985 | 0.77 | CA1 (0.57) | CA1MEN1KMT2ALMNAHTT | |
| SCHEMBL3467516 | 0.76 | L3MBTL1 (0.71) | CA1MEN1MAPTKMT2AABL1 | |
| SCHEMBL3467359 | 0.74 | ALDH1A1 (0.52) | CA1MEN1MAPTKMT2ALMNA | |
| SCHEMBL3466833 | 0.73 | ALDH1A1 (0.54) | MEN1MAPTKMT2ALMNAALDH1A1 | |
| SCHEMBL3468791 | 0.72 | ALDH1A1 (0.55) | CA1MEN1MAPTKMT2ALMNA | |
| SCHEMBL3468523 | 0.72 | ALDH1A1 (0.52) | CA1MEN1MAPTKMT2ALMNA | |
| SCHEMBL3466755 | 0.72 | ALDH1A1 (0.62) | CA1MEN1MAPTKMT2ALMNA | |
| SCHEMBL5389976 | 0.72 | ALDH1A1 (0.58) | CA1MEN1KMT2ALMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |