Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 8/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SCN1A | P35498 | 1/20 | 0.42 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467362 | 0.94 | CA1 (0.54) | CA1RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3466778 | 0.81 | CA1 (0.53) | CA1RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3467102 | 0.80 | CA1 (0.61) | CA1RAB9ASMN1; SMN2NPC1MEN1 | |
| SCHEMBL3468755 | 0.80 | CA1 (0.57) | CA1RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3467663 | 0.77 | CA1 (0.74) | CA1ALDH1A1HTTMEN1LMNA | |
| SCHEMBL3466962 | 0.73 | RAB9A (0.53) | CA1RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3467834 | 0.72 | MEN1 (0.48) | CA1ALDH1A1HTTMEN1LMNA | |
| SCHEMBL3466755 | 0.71 | ALDH1A1 (0.62) | CA1ALDH1A1HTTMEN1LMNA | |
| SCHEMBL3467177 | 0.71 | RAB9A (0.64) | CA1RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL3468245 | 0.69 | ALDH1A1 (0.52) | RAB9ASMN1; SMN2NPC1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |