Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467631 | 0.86 | ALDH1A1 (0.58) | ALDH1A1HSD17B10CA1CA2HPGD | |
| SCHEMBL3466980 | 0.77 | ALDH1A1 (0.65) | ALDH1A1HSD17B10CA1CA2HPGD | |
| SCHEMBL3467587 | 0.77 | ALDH1A1 (0.52) | ALDH1A1HSD17B10CA1CA2HPGD | |
| SCHEMBL3467234 | 0.74 | MEN1 (0.48) | ALDH1A1HSD17B10CA1CA2MEN1 | |
| SCHEMBL3467834 | 0.74 | MEN1 (0.48) | ALDH1A1HSD17B10CA1CA2MEN1 | |
| SCHEMBL3467474 | 0.73 | ALDH1A1 (0.62) | ALDH1A1HSD17B10CA1CA2HPGD | |
| SCHEMBL3467863 | 0.73 | ALDH1A1 (0.45) | ALDH1A1HSD17B10CA1CA2HPGD | |
| SCHEMBL3467783 | 0.72 | ALDH1A1 (0.55) | ALDH1A1HSD17B10HPGDMEN1KMT2A | |
| SCHEMBL3466719 | 0.71 | SMN1; SMN2 (0.59) | ALDH1A1HSD17B10HPGDMEN1KMT2A | |
| SCHEMBL3467586 | 0.70 | ALDH1A1 (0.56) | ALDH1A1HSD17B10CA1CA2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |