Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | GGT1 | P19440 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467863 | 0.92 | ALDH1A1 (0.45) | ALDH1A1HSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3467372 | 0.79 | ALDH1A1 (0.56) | ALDH1A1HSD17B10MEN1KMT2ACA1 | |
| SCHEMBL3467037 | 0.78 | ALDH1A1 (0.56) | ALDH1A1HSD17B10MEN1KMT2ACA1 | |
| SCHEMBL3467562 | 0.78 | ALDH1A1 (0.54) | ALDH1A1HSD17B10MEN1KMT2ACA1 | |
| SCHEMBL3468086 | 0.77 | ALDH1A1 (0.60) | ALDH1A1HSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3466719 | 0.76 | SMN1; SMN2 (0.59) | ALDH1A1HSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3467984 | 0.76 | ALDH1A1 (0.52) | ALDH1A1HSD17B10MEN1KMT2ACA1 | |
| SCHEMBL3467586 | 0.75 | ALDH1A1 (0.56) | ALDH1A1HSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3466980 | 0.73 | ALDH1A1 (0.65) | ALDH1A1HSD17B10SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3467474 | 0.71 | ALDH1A1 (0.62) | ALDH1A1HSD17B10SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |