SCHEMBL3468518

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3467557	0.96	DYRK1B (0.43)	ESR1HPGDPTGS2RECQLCA1
	SCHEMBL3468296	0.86	LMNA (0.50)	HPGDPTGS2RECQLCA1CA2
	SCHEMBL3468101	0.84	UQCRB (0.51)	GAALMNASMN1; SMN2GFERALDH1A1
	SCHEMBL3468408	0.82	ESR1 (0.56)	ESR1HPGDPTGS2CA1CA2
	SCHEMBL3468105	0.82	ENPP2 (0.53)	ESR1PTGS2
	SCHEMBL3467956	0.80	ALDH1A1 (0.56)	ESR1HPGDCA1CA2GAA
	SCHEMBL3468801	0.78	ENPP2 (0.49)	ESR1PTGS2
	SCHEMBL3468569	0.77	ESR1 (0.59)	ESR1HPGDCA1CA2LMNA
	Gsk-232802 SCHEMBL3467757	0.77	ESR1 (0.55)	ESR1RECQLCA1CA2SMN1; SMN2
	SCHEMBL3468652	0.76	ALDH1A1 (0.51)	ESR1HPGDCA1CA2DYRK1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.