Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | PTPRE | P23469 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | GLS | O94925 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | USP2 | O75604 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21450201 | 0.87 | MAPT (0.73) | TP53MAPTALDH1A1LMNAHPGD | |
| SCHEMBL3467104 | 0.83 | L3MBTL1 (0.65) | ALDH1A1SMN1; SMN2L3MBTL1GLSPOLB | |
| SCHEMBL3467988 | 0.82 | SMN1; SMN2 (0.69) | TP53MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL3466732 | 0.81 | NPC1 (0.72) | MAPTALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL29047587 | 0.79 | L3MBTL1 (0.60) | TP53ALDH1A1SMN1; SMN2L3MBTL1POLB | |
| SCHEMBL12793509 | 0.78 | MEN1 (0.76) | TP53MAPTALDH1A1LMNAHPGD | |
| SCHEMBL12838825 | 0.75 | ALDH1A1 (0.72) | MAPTALDH1A1LMNAHPGDSMN1; SMN2 | |
| SCHEMBL21450180 | 0.74 | MAPT (0.68) | TP53MAPTALDH1A1LMNAHPGD | |
| SCHEMBL21436991 | 0.74 | NPSR1 (0.77) | MAPTALDH1A1LMNAHPGDL3MBTL1 | |
| SCHEMBL20887240 | 0.74 | KDM4E (0.79) | MAPTALDH1A1LMNAHSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | claimed |
| WO-2010073011-A2 | COMPOUNDS USEFUL AS MEDICAMENTS | BETAGENON AB (SE) | 2010-07-01 | — | — | WO | disclosed |