SCHEMBL4523181

SCHEMBL4523181

CCSc1ccc(N)cc1

nearest known ligand 0.52

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 9/20 0.52
MAOA P21397 1/20 0.52
TSHR P16473 3/20 0.50
CYP3A4 P08684 2/20 0.50
MAPK1 P28482 2/20 0.50
ALDH1A1 P00352 3/20 0.47
MEN1 O00255 3/20 0.47
KMT2A Q03164 3/20 0.47
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
MAPT P10636 1/20 0.42
TDP1 Q9NUW8 3/20 0.41
KDM4E B2RXH2 1/20 0.41
PSMD14 O00487 1/20 0.41
RECQL P46063 1/20 0.41
GFER P55789 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
ACHE P22303 1/20 0.39
GAA P10253 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8897816 0.97 SLC6A4 (0.50) SLC6A4MAOATSHRCYP3A4MAPK1
SCHEMBL3781960 0.93 TDP1 (0.50) SLC6A4MAOATSHRCYP3A4MAPK1
SCHEMBL346860 0.86 SLC6A4 (0.56) SLC6A4MAOAMAPK1ALDH1A1NPC1
SCHEMBL8809913 0.80 CA12 (0.57) MAOATSHRCYP3A4MAPK1ALDH1A1
SCHEMBL12172517 0.78 CYP3A4 (0.55) TSHRCYP3A4MAPK1ALDH1A1MEN1
SCHEMBL8591154 0.78 SLC6A4 (0.50) SLC6A4MAOAMAPK1ALDH1A1MEN1
SCHEMBL1808815 0.78 CYP3A4 (0.55) MAOATSHRCYP3A4MAPK1ALDH1A1
SCHEMBL10316183 0.78 SLC6A4 (0.50) SLC6A4MAOATSHRCYP3A4MAPK1
SCHEMBL9793575 0.78 SLC6A4 (0.50) SLC6A4MAOANPC1RAB9A
SCHEMBL3785538 0.77 GCK (0.38) SLC6A4MAOATSHRCYP3A4MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3396028-B1 DIRECT ELECTROCHEMICAL SYNTHESIS OF DOPED CONDUCTIVE POLYMERS ON METAL ALLOYS BOEING CO (US) 2022-04-06 EP claimed
US-7211202-B2 Process to make a conductive composition of a fluorinated polymer which contains polyaniline ATOFINA (FR) 2007-05-01 US claimed
EP-1428857-B1 Process to make a conductive composition of a fluorinated polymer which contains polyaniline ARKEMA FRANCE (FR) 2007-01-31 EP claimed
CN-119490443-A Photoresist main body material, preparation method thereof, photoresist composition containing photoresist main body material and photoresist coating 中国科学院理化技术研究所 2025-02-21 CN disclosed
EP-4247797-A1 2-PHENYLBENZOTRIAZOL-5-AMINE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS (HBV) INFECTION F. Hoffmann-La Roche AG (CH) 2023-09-27 EP disclosed
US-11760775-B2 Steroids and protein-conjugates thereof REGENERON PHARMACEUTICALS, INC. 2023-09-19 US disclosed
US-20230286927-A1 2-PHENYLBENZOTRIAZOL-5-AMINE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS (HBV) INFECTION HOFFMANN-LA ROCHE INC. (US) 2023-09-14 US disclosed
US-20230286927-A1 2-PHENYLBENZOTRIAZOL-5-AMINE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS (HBV) INFECTION HOFFMANN-LA ROCHE INC. (US) 2023-09-14 US disclosed
US-20230286927-A1 2-PHENYLBENZOTRIAZOL-5-AMINE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS (HBV) INFECTION HOFFMANN-LA ROCHE INC. (US) 2023-09-14 US disclosed
WO-2022106588-A1 2-PHENYLBENZOTRIAZOL-5-AMINE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS (HBV) INFECTION F. HOFFMANN-LA ROCHE AG (CH) 2022-05-27 WO disclosed
WO-2022106588-A1 2-PHENYLBENZOTRIAZOL-5-AMINE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS (HBV) INFECTION F. HOFFMANN-LA ROCHE AG (CH) 2022-05-27 WO disclosed
US-5278213-A Low viscosity solution ALLIED SIGNAL INC. (US) 1994-01-11 US disclosed
US-5019134-A Triphenodioxazines IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-05-28 US disclosed
EP-0356014-A1 Reactive Dyes ZENECA LIMITED (GB) 1990-02-28 EP disclosed
EP-0315862-A2 Aromatically fluorinated fluoromethoxy- and fluoromethylthio-amino benzenes and their preparation BAYER AG (DE) 1989-05-17 EP disclosed
EP-0201811-A1 7-Oxabicycloheptane substituted aryl amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction E.R. Squibb & Sons, Inc. (US) 1986-11-20 EP disclosed
US-4607048-A 7-oxabicycloheptane substituted aryl amino prostaglandin analogs and their use in inhibiting platelet aggregation and bronchoconstriction E. R. SQUIBB & SONS, INC. (US) 1986-08-19 US disclosed
US-4303673-A N-Propionylsarcosineanilides, process for their preparation, and pharmaceutical compositions containing them A. NATTERMANN & CIE. GMBH (DE) 1981-12-01 US disclosed
US-4150029-A ANTIDEPRESSANTS DELALANDE S.A. (FR) 1979-04-17 US disclosed
US-4036849-A ANTIMICROBIAL AMERICAN CYANAMID COMPANY (US) 1977-07-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230286927-A1 2-PHENYLBENZOTRIAZOL-5-AMINE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS (HBV) INFECTION HAVCR2, NR1H4, SLC10A1 SLC6A4 2382/4885MAOA 707/4885TSHR 965/4885
US-11760775-B2 Steroids and protein-conjugates thereof SERPINA6, NR3C1, NR3C2 SLC6A4 3841/4885MAOA 4635/4885TSHR 809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.