Diphenylmethane

Diphenylmethane

SCHEMBL3468648

CC(CN=C=O)N=C=O.OCCO.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.36
TSHR P16473 2/20 0.36
CALM1 P0DP23 1/20 0.35
HPGD P15428 1/20 0.34
NPY5R Q15761 1/20 0.34
CYP3A4 P08684 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
TRPA1 O75762 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
PTPN1 P18031 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
PLA2G10 O15496 1/20 0.33
PLA2G2A P14555 1/20 0.33
NPC1 O15118 2/20 0.32
RAB9A P51151 2/20 0.32
ADRA2B P18089 1/20 0.32
ADRA2C P18825 1/20 0.32
SLC6A2 P23975 1/20 0.32
HTR2A P28223 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL3468312 0.87 KDM4E (0.33) LMNATSHRSMN1; SMN2MEN1KMT2A
Ethylene Glycol SCHEMBL3267802 0.82
Ethylene Glycol SCHEMBL10604368 0.82
Diphenylmethane SCHEMBL3468615 0.77 CALM1 (0.46) LMNATSHRCALM1HPGDCYP3A4
SCHEMBL44073 0.75
Ether SCHEMBL10884068 0.73 ALDH1A1 (0.30)
SCHEMBL27515553 0.72 SLC6A2 (0.48) TSHRHPGDMEN1KMT2AADRA2B
SCHEMBL2729032 0.72 SLC6A2 (0.48) TSHRHPGDMEN1KMT2AADRA2B
SCHEMBL21056125 0.72 SLC6A2 (0.48) TSHRHPGDMEN1KMT2AADRA2B
Hydrazine SCHEMBL22444473 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2055327-B1 Antimicrobial lubricious coating COVIDIEN LP (US) 2013-12-11 EP disclosed
US-7820734-B2 Antimicrobial lubricious coating TYCO HEALTHCARE GROUP LP (US) 2010-10-26 US disclosed
EP-2055327-A1 Antimicrobial lubricious coating Tyco Healthcare Group LP (US) 2009-05-06 EP disclosed
US-20080085949-A1 ANTIMICROBIAL LUBRICIOUS COATING KPR U.S., LLC 2008-04-10 US disclosed
WO-1995006670-A1 LOW FRICTION, HYDROPHILIC, BIOCOMPATIBLE COMPOSITIONS NEPERA, INC. (US) 1995-03-09 WO disclosed