Diphenylmethane

Diphenylmethane

SCHEMBL3468615

O=C=NCCN=C=O.OCCO.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CALM1 P0DP23 1/20 0.46
LMNA P02545 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
PLA2G10 O15496 1/20 0.40
PLA2G2A P14555 1/20 0.40
TSHR P16473 2/20 0.39
CYP3A4 P08684 2/20 0.39
SLC22A2 O15244 1/20 0.39
MIF P14174 3/20 0.37
TRPA1 O75762 2/20 0.37
IDH1 O75874 1/20 0.37
CYP2E1 P05181 1/20 0.37
CYP2A6 P11509 1/20 0.37
HIF1A Q16665 1/20 0.37
CYP2A13 Q16696 1/20 0.37
EPAS1 Q99814 1/20 0.37
CYP2C9 P11712 1/20 0.36
HNF4A P41235 1/20 0.36
PTPN1 P18031 1/20 0.36
BCL2 P10415 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diphenylmethane SCHEMBL10971266 0.92 CALM1 (0.55) CALM1LMNAPLA2G10PLA2G2ATSHR
Biphenyl SCHEMBL23923632 0.84 ALDH1A1 (0.38) LMNATDP1TSHRHIF1APTPN1
Diphenylmethane SCHEMBL8726121 0.83 ALDH1A1 (0.38) CALM1LMNATSHRMIFALDH1A1
Diphenylmethane SCHEMBL28176599 0.82 MIF (0.50) CALM1LMNAPLA2G10PLA2G2ATSHR
Phenol SCHEMBL11151921 0.82 TDP1 (0.44) LMNATDP1MIFBCL2L1ALDH1A1
Toluene SCHEMBL3469198 0.81 LMNA (0.42) LMNATDP1TSHRCYP3A4CES2
Diphenylmethane SCHEMBL8938749 0.79 CALM1 (0.55) CALM1LMNAPLA2G10PLA2G2ATSHR
Diphenylmethane SCHEMBL27961286 0.79 CALM1 (0.55) CALM1LMNATDP1PLA2G10PLA2G2A
Diphenylmethane SCHEMBL1014928 0.79 CALM1 (0.55) CALM1LMNATDP1PLA2G10PLA2G2A
Diphenylmethane SCHEMBL4556684 0.78 CALM1 (0.75) CALM1LMNATDP1PLA2G10PLA2G2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015187632-A1 POLYMERIC FILMS COMPRISING ANTIMICROBIAL AGENTS AVERY DENNISON CORPORATION (US) 2015-12-10 WO disclosed
EP-2055327-B1 Antimicrobial lubricious coating COVIDIEN LP (US) 2013-12-11 EP disclosed
US-7820734-B2 Antimicrobial lubricious coating TYCO HEALTHCARE GROUP LP (US) 2010-10-26 US disclosed
EP-2055327-A1 Antimicrobial lubricious coating Tyco Healthcare Group LP (US) 2009-05-06 EP disclosed
US-20080085949-A1 ANTIMICROBIAL LUBRICIOUS COATING KPR U.S., LLC 2008-04-10 US disclosed
EP-0520160-A1 Process for antimicrobial treatment of polyurethane BOC HEALTH CARE, Inc. (US) 1992-12-30 EP disclosed