Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4244577 | 0.76 | DAO (0.44) | CNR1HPGDALDH1A1ALOX12HTT | |
| SCHEMBL14198883 | 0.73 | ALDH1A1 (0.41) | CNR1HPGDALDH1A1ALOX12HTT | |
| SCHEMBL9454295 | 0.72 | CYP2A6 (0.45) | — | |
| SCHEMBL3711956 | 0.71 | HPGD (0.34) | CNR1HPGDALDH1A1ALOX12HTT | |
| SCHEMBL513970 | 0.70 | ACHE (0.40) | HPGDALDH1A1KDM4E | |
| SCHEMBL4244869 | 0.69 | CYP2A6 (0.48) | KDM4E | |
| SCHEMBL18869535 | 0.69 | ALAD (0.52) | CNR1HPGDALDH1A1ALOX12KDM4E | |
| SCHEMBL13802803 | 0.69 | ALAD (0.52) | CNR1ALDH1A1HTTKMT2A | |
| SCHEMBL883778 | 0.69 | ALDH1A1 (0.44) | CNR1HPGDALDH1A1ALOX12HTT | |
| SCHEMBL457428 | 0.69 | ALDH1A1 (0.43) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010085968-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE AS HIF-INHIBITORS | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2010-08-05 | — | — | WO | disclosed |
| WO-2010076034-A1 | TOLUIDINE SULFONAMIDES AND THEIR USE AS-INHIBITORS | EUROPEAN MOLECULAR BIOLOGY LABORATORY (EMBL) (DE) | 2010-07-08 | — | — | WO | disclosed |