SCHEMBL3469030

SCHEMBL3469030

CCCCC(CC)Cn1cccc1-c1nc(-c2ccc(O)c(C)c2O)nc(-c2ccc(O)c(C)c2O)n1

nearest known ligand 0.32

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 1/20 0.32
LMNA P02545 3/20 0.31
GAA P10253 4/20 0.31
KDM4E B2RXH2 3/20 0.31
HSD17B10 Q99714 3/20 0.31
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
ALDH1A1 P00352 2/20 0.31
HPGD P15428 2/20 0.31
TSHR P16473 2/20 0.31
XBP1 P17861 1/20 0.31
PPARG P37231 1/20 0.31
NCOA3 Q9Y6Q9 1/20 0.31
MAPT P10636 3/20 0.31
MAPK1 P28482 3/20 0.31
HTT P42858 1/20 0.31
PAX8 Q06710 1/20 0.31
MCL1 Q07820 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13282831 0.89
SCHEMBL3469062 0.86 LMNA (0.32) LMNAHSD17B10ALDH1A1TSHRMAPK1
SCHEMBL3469027 0.84 PRSS1 (0.32)
SCHEMBL3363585 0.81 CA12 (0.34) LMNAGAAKDM4EHSD17B10MEN1
SCHEMBL3468817 0.81 LMNA (0.32) LMNAALDH1A1MAPK1
SCHEMBL13283103 0.79
SCHEMBL3469064 0.79 DYRK1A (0.37) GAAKDM4EHSD17B10MEN1KMT2A
SCHEMBL3360208 0.76 ICMT (0.35) GAAHSD17B10TSHRPPARGMAPT
SCHEMBL3468902 0.76 ALDH1A1 (0.32) LMNAGAAKDM4EMEN1KMT2A
SCHEMBL3360359 0.75 KDM4E (0.34) LMNAGAAKDM4EHSD17B10MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010081835-A2 BIS-RESORCINYL-TRIAZINE DERIVATIVES AS PROTECTING AGENTS AGAINST UV RADIATION ISDIN, S. A. (ES) 2010-07-22 WO disclosed