SCHEMBL3360359

SCHEMBL3360359

CCCCC(CC)Cn1c(C)c(-c2nc(-c3ccc(O)c(C)c3O)nc(-c3ccc(O)c(C)c3O)n2)c2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.34
ALDH1A1 P00352 6/20 0.34
HSD17B10 Q99714 4/20 0.34
HPGD P15428 3/20 0.34
GAA P10253 3/20 0.34
MEN1 O00255 1/20 0.34
TSHR P16473 1/20 0.34
XBP1 P17861 1/20 0.34
PPARG P37231 1/20 0.34
KMT2A Q03164 1/20 0.34
NCOA3 Q9Y6Q9 1/20 0.34
MAPT P10636 3/20 0.34
MAPK1 P28482 1/20 0.34
CASP1 P29466 1/20 0.34
CASP7 P55210 1/20 0.34
LMNA P02545 4/20 0.33
TP53 P04637 1/20 0.32
BCL2L1 Q07817 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
RCE1 Q9Y256 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3360163 0.88 KDM4E (0.33) KDM4EALDH1A1HSD17B10HPGDGAA
SCHEMBL3360821 0.86 KDM4E (0.38) KDM4EHSD17B10GAAMEN1KMT2A
SCHEMBL3363585 0.83 CA12 (0.34) KDM4EALDH1A1HSD17B10HPGDGAA
SCHEMBL3360831 0.80 ALDH1A1 (0.38) KDM4EALDH1A1HSD17B10HPGDGAA
SCHEMBL3360827 0.77 KDM4E (0.35) KDM4EHSD17B10MEN1KMT2AMAPT
SCHEMBL13282870 0.76 CA12 (0.34) KDM4EALDH1A1HSD17B10HPGDGAA
SCHEMBL3469030 0.75 TYR (0.32) KDM4EALDH1A1HSD17B10HPGDGAA
SCHEMBL3469064 0.75 DYRK1A (0.37) KDM4EALDH1A1HSD17B10HPGDGAA
SCHEMBL3360208 0.74 ICMT (0.35) HSD17B10GAATSHRPPARGMAPT
SCHEMBL3361773 0.72 CA2 (0.33) ALDH1A1MEN1KMT2AMAPTMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2210887-A1 Bis resorcinyl triazine derivatives as protecting agents against UV radiation ISDIN, S.A. (ES) 2010-07-28 EP disclosed
WO-2010081835-A2 BIS-RESORCINYL-TRIAZINE DERIVATIVES AS PROTECTING AGENTS AGAINST UV RADIATION ISDIN, S. A. (ES) 2010-07-22 WO disclosed