Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | KEAP1 | Q14145 | 5/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.31 |
| ▸ | NAAA | Q02083 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylmethane SCHEMBL8726121 | 0.87 | ALDH1A1 (0.38) | ALDH1A1TSHRLMNAMAOAMAOB | |
| Biphenyl SCHEMBL3012620 | 0.87 | NAAA (0.38) | ALDH1A1MAPTTRPM8MEN1KMT2A | |
| Toluene SCHEMBL3469198 | 0.84 | LMNA (0.42) | MAPTTSHRLMNAALOX12ACHE | |
| Ether SCHEMBL11056367 | 0.84 | ALDH1A1 (0.36) | ALDH1A1MIFNAAA | |
| Biphenyl SCHEMBL3023954 | 0.83 | ALDH1A1 (0.36) | ALDH1A1MAPTLMNATRPM8MEN1 | |
| Toluene SCHEMBL27815423 | 0.82 | LMNA (0.44) | TSHRLMNAALOX12ACHEMEN1 | |
| Toluene SCHEMBL28180326 | 0.82 | LMNA (0.44) | TSHRLMNAALOX12ACHEMEN1 | |
| Toluene SCHEMBL11494092 | 0.80 | TSHR (0.50) | ALDH1A1MAPTTSHRLMNAALOX12 | |
| Toluene SCHEMBL28100339 | 0.80 | LMNA (0.38) | TSHRLMNAALOX12ACHEMAOA | |
| Toluene SCHEMBL1508677 | 0.78 | LMNA (0.39) | TSHRLMNAALOX12ACHEMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2055327-B1 | Antimicrobial lubricious coating | COVIDIEN LP (US) | 2013-12-11 | — | — | EP | disclosed |
| US-7820734-B2 | Antimicrobial lubricious coating | TYCO HEALTHCARE GROUP LP (US) | 2010-10-26 | — | — | US | disclosed |
| EP-2055327-A1 | Antimicrobial lubricious coating | Tyco Healthcare Group LP (US) | 2009-05-06 | — | — | EP | disclosed |
| US-20080085949-A1 | ANTIMICROBIAL LUBRICIOUS COATING | KPR U.S., LLC | 2008-04-10 | — | — | US | disclosed |
| EP-0818207-A2 | Medical article | The BOC Group plc (GB) | 1998-01-14 | — | — | EP | disclosed |
| EP-0799623-A2 | Medical article with a lubricious coating | The BOC Group plc (GB) | 1997-10-08 | — | — | EP | disclosed |