Diphenylmethane

Diphenylmethane

SCHEMBL8726121

CCOCC.O=C=NCCCCN=C=O.OCCO.c1ccc(Cc2ccccc2)cc1

nearest known ligand 0.38

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.38
MIF P14174 3/20 0.36
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
NAAA Q02083 3/20 0.36
KEAP1 Q14145 5/20 0.35
NFE2L2 Q16236 5/20 0.35
LMNA P02545 1/20 0.35
CALM1 P0DP23 1/20 0.34
LTA4H P09960 3/20 0.34
TSHR P16473 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toluene SCHEMBL3469158 0.87 ALDH1A1 (0.34) ALDH1A1MIFMAOAMAOBNAAA
Biphenyl SCHEMBL3012620 0.85 NAAA (0.38) ALDH1A1NAAA
Diphenylmethane SCHEMBL3468615 0.83 CALM1 (0.46) ALDH1A1MIFLMNACALM1TSHR
Ether SCHEMBL11056367 0.83 ALDH1A1 (0.36) ALDH1A1MIFNAAA
Biphenyl SCHEMBL3023954 0.82 ALDH1A1 (0.36) ALDH1A1NAAALMNA
Diphenylmethane SCHEMBL28176599 0.81 MIF (0.50) ALDH1A1MIFMAOAMAOBNAAA
Diphenylmethane SCHEMBL3882710 0.77 NAAA (0.46) MIFMAOAMAOBNAAAKEAP1
Diphenylmethane SCHEMBL10971266 0.76 CALM1 (0.55) ALDH1A1MIFNAAALMNACALM1
Ether SCHEMBL11819479 0.76 NAAA (0.34) ALDH1A1MIFNAAAKEAP1NFE2L2
Benzyl Alcohol SCHEMBL11378323 0.75 TSHR (0.44) ALDH1A1MIFMAOAMAOBNAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015187632-A1 POLYMERIC FILMS COMPRISING ANTIMICROBIAL AGENTS AVERY DENNISON CORPORATION (US) 2015-12-10 WO disclosed
EP-0818207-A2 Medical article The BOC Group plc (GB) 1998-01-14 EP disclosed
EP-0799623-A2 Medical article with a lubricious coating The BOC Group plc (GB) 1997-10-08 EP disclosed
EP-0520160-A1 Process for antimicrobial treatment of polyurethane BOC HEALTH CARE, Inc. (US) 1992-12-30 EP disclosed
US-4849286-A BLEND OF POLYURETHANE AND POLYVINYLPYRROLIDONE JAMES RIVER GRAPHICS, INC. (US) 1989-07-18 US disclosed