Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 0.79 |
| ▸ | FLT3 | P36888 | 14/20 | 0.79 |
| ▸ | KIT | P10721 | 12/20 | 0.79 |
| ▸ | CSF1R | P07333 | 10/20 | 0.79 |
| ▸ | FLT4 | P35916 | 10/20 | 0.79 |
| ▸ | FLT1 | P17948 | 9/20 | 0.79 |
| ▸ | LYN | P07948 | 8/20 | 0.79 |
| ▸ | LCK | P06239 | 8/20 | 0.79 |
| ▸ | SRC | P12931 | 7/20 | 0.79 |
| ▸ | BLK | P51451 | 7/20 | 0.79 |
| ▸ | FYN | P06241 | 5/20 | 0.79 |
| ▸ | PLK4 | O00444 | 4/20 | 0.77 |
| ▸ | AURKA | O14965 | 4/20 | 0.77 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.77 |
| ▸ | MET | P08581 | 4/20 | 0.77 |
| ▸ | PRKACA | P17612 | 4/20 | 0.77 |
| ▸ | RPS6KB1 | P23443 | 4/20 | 0.77 |
| ▸ | CSNK1D | P48730 | 4/20 | 0.77 |
| ▸ | STK3 | Q13188 | 4/20 | 0.77 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL15808658 | 0.99 | KDR (0.78) | KDRFLT3KITCSF1RFLT4 | |
| SCHEMBL16303676 | 0.90 | KDR (0.80) | KDRFLT3KITCSF1RFLT4 | |
| SCHEMBL420765 | 0.88 | KDR (1.00) | KDRFLT3KITCSF1RFLT4 | |
| SCHEMBL423705 | 0.88 | KDR (0.80) | KDRFLT3KITCSF1RFLT4 | |
| SCHEMBL421934 | 0.87 | KDR (0.82) | KDRFLT3KITCSF1RFLT4 | |
| Linifanib SCHEMBL29375368 | 0.87 | KDR (1.00) | KDRFLT3KITCSF1RFLT4 | |
| Linifanib SCHEMBL93804 | 0.87 | KDR (1.00) | KDRFLT3KITCSF1RFLT4 | |
| SCHEMBL424019 | 0.87 | KDR (0.79) | KDRFLT3KITCSF1RFLT4 | |
| Linifanib SCHEMBL1880038 | 0.86 | KDR (0.98) | KDRFLT3KITCSF1RFLT4 | |
| SCHEMBL16303695 | 0.86 | KDR (0.78) | KDRFLT3KITCSF1RFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160264969-A1 | METHODS FOR TREATING OR PREVENTING OPHTHALMOLOGICAL DISEASES | OPHTHOTECH CORPORATION | 2016-09-15 | — | — | US | disclosed |
| US-20100227904-A1 | Pharmaceutical Composition for Delivery of Receptor Tyrosine Kinase Inhibiting (RTKi) Compounds to the Eye | ALCON RESEARCH, LTD. (US) | 2010-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160264969-A1 | METHODS FOR TREATING OR PREVENTING OPHTHALMOLOGICAL DISEASES | VEGFA, PDGFA, PGF | KDR 10/4885FLT3 2026/4885KIT 288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.