Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | ALKBH1 | Q13686 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | SCD5 | Q86SK9 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | FSCN1 | Q16658 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | JAK3 | P52333 | 1/20 | 0.37 |
| ▸ | TAS2R8 | Q9NYW2 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3097443 | 0.85 | ALDH1A1 (0.55) | KLKB1HDAC1SCDSCD5LMNA | |
| SCHEMBL3100595 | 0.84 | KLKB1 (0.38) | KLKB1HDAC1ADORA2BSCDSCD5 | |
| SCHEMBL3469650 | 0.83 | LMNA (0.53) | SCD5LMNAALDH1A1MAPTPOLB | |
| SCHEMBL3100268 | 0.81 | KLKB1 (0.43) | KLKB1HDAC1ADORA2BHDAC7ALKBH1 | |
| SCHEMBL15014141 | 0.79 | ADORA2B (0.46) | KLKB1HDAC1ADORA2BLMNAALDH1A1 | |
| SCHEMBL3091791 | 0.79 | MAPT (0.43) | KLKB1HDAC1ADORA2BHDAC7LMNA | |
| SCHEMBL3100451 | 0.78 | ALDH1A1 (0.39) | KLKB1ADORA2BSCDSCD5FSCN1 | |
| SCHEMBL3097709 | 0.78 | KLKB1 (0.45) | KLKB1HDAC1ADORA2BHDAC7ALKBH1 | |
| Hydrochloric Acid SCHEMBL21491801 | 0.78 | MAPT (0.46) | KLKB1HDAC1ADORA2BHDAC7LMNA | |
| SCHEMBL13181121 | 0.76 | ADORA2B (0.47) | KLKB1HDAC1ADORA2BHDAC7LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2172450-B9 | NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2014-10-08 | — | — | EP | disclosed |
| EP-2172450-B1 | NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | MITSUBISHI TANABE PHARMA CORP (JP) | 2013-10-16 | — | — | EP | disclosed |
| EP-2172450-A1 | NOVEL MALONIC ACID SULFONAMIDE DERIVATIVE AND PHARMACEUTICAL USE THEREOF | Mitsubishi Tanabe Pharma Corporation (JP) | 2010-04-07 | — | — | EP | disclosed |