Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 5/20 | 0.38 |
| ▸ | KDR | P35968 | 2/20 | 0.38 |
| ▸ | FLT1 | P17948 | 2/20 | 0.38 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.38 |
| ▸ | FLT3 | P36888 | 1/20 | 0.38 |
| ▸ | ULK1 | O75385 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.36 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.36 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.36 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.36 |
| ▸ | EED | O75530 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3470512 | 0.89 | SYK (0.49) | PRKD1SYKEGFRFGFR2FLT3 | |
| SCHEMBL11939102 | 0.84 | TTK (0.45) | PRKD1SYKTTKPTK6TNK2 | |
| SCHEMBL3469690 | 0.83 | PRKD1 (0.44) | PRKD1SYKEGFRKDRFLT1 | |
| SCHEMBL3470208 | 0.82 | FGFR2 (0.40) | PRKD1SYKEGFRKDRFLT1 | |
| SCHEMBL3469529 | 0.82 | PRKD1 (0.41) | PRKD1SYKEGFRKDRFLT1 | |
| SCHEMBL11939505 | 0.77 | FLT1 (0.47) | PRKD1SYKEGFRKDRFLT1 | |
| SCHEMBL5394301 | 0.76 | FLT3 (0.49) | FLT3BRD4TTK | |
| SCHEMBL3470478 | 0.76 | MAPKAPK5 (0.43) | PRKD1SYKEGFRKDRFLT1 | |
| SCHEMBL3469745 | 0.76 | ABL1 (0.51) | SYKEGFRFGFR2FLT3ULK1 | |
| SCHEMBL1674087 | 0.74 | MAPKAPK5 (0.60) | SYKEGFRFGFR2FLT3PTK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |