Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 3/20 | 0.39 |
| ▸ | FLT1 | P17948 | 3/20 | 0.39 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | MAPKAPK5 | Q8IW41 | 2/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3469690 | 0.89 | PRKD1 (0.44) | FGFR2FLT3GRM4CYP1A2PRKD1 | |
| SCHEMBL3469529 | 0.84 | PRKD1 (0.41) | FGFR2FLT3PRKD1SYKEGFR | |
| SCHEMBL3470512 | 0.84 | SYK (0.49) | FGFR2FLT3PRKD1SYKEGFR | |
| SCHEMBL3469679 | 0.82 | PRKD1 (0.40) | FGFR2FLT3PRKD1SYKEGFR | |
| SCHEMBL3470478 | 0.82 | MAPKAPK5 (0.43) | FGFR2FLT3GRM4PRKD1SYK | |
| SCHEMBL11939505 | 0.81 | FLT1 (0.47) | FGFR2FLT3PRKD1SYKEGFR | |
| SCHEMBL3468104 | 0.78 | FGFR2 (0.42) | FGFR2FLT3GRM4PRKD1SYK | |
| SCHEMBL14537044 | 0.78 | AURKA (0.45) | FGFR2FLT3PRKD1SYKEGFR | |
| SCHEMBL8241606 | 0.78 | AURKA (0.58) | FGFR2FLT3SYKEGFRMAPKAPK5 | |
| SCHEMBL3471097 | 0.77 | PIP4K2A (0.44) | CYP1A2SYKMAPKAPK5PTK6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |