Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK5 | Q8IW41 | 3/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 3/20 | 0.42 |
| ▸ | FLT1 | P17948 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.42 |
| ▸ | FLT3 | P36888 | 1/20 | 0.42 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.41 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.40 |
| ▸ | SYK | P43405 | 2/20 | 0.40 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TTK | P33981 | 1/20 | 0.38 |
| ▸ | EED | O75530 | 1/20 | 0.38 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | LYN | P07948 | 1/20 | 0.37 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3471097 | 0.84 | PIP4K2A (0.44) | MAPKAPK5FYNPTK6SYKAURKA | |
| SCHEMBL3468104 | 0.83 | FGFR2 (0.42) | MAPKAPK5EGFRFLT1FGFR2FLT3 | |
| SCHEMBL3470208 | 0.82 | FGFR2 (0.40) | MAPKAPK5EGFRFLT1KDRFGFR2 | |
| SCHEMBL14767444 | 0.81 | TTK (0.54) | MAPKAPK5FYNPTK6AURKAAURKB | |
| SCHEMBL3469690 | 0.81 | PRKD1 (0.44) | MAPKAPK5EGFRFLT1KDRFGFR2 | |
| SCHEMBL14537044 | 0.81 | AURKA (0.45) | MAPKAPK5EGFRFLT1FGFR2FLT3 | |
| SCHEMBL8241606 | 0.81 | AURKA (0.58) | MAPKAPK5EGFRFGFR2FLT3PTK6 | |
| SCHEMBL12409307 | 0.81 | FYN (0.47) | MAPKAPK5FYNPTK6AURKAAURKB | |
| SCHEMBL3469745 | 0.80 | ABL1 (0.51) | MAPKAPK5EGFRFGFR2FLT3PTK6 | |
| SCHEMBL11939505 | 0.80 | FLT1 (0.47) | MAPKAPK5EGFRFLT1KDRFGFR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |