SCHEMBL3469802

SCHEMBL3469802

ClC1=C[CH]c2ccccc2C1

nearest known ligand 0.36

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 1/20 0.36
CYP11B2 P19099 2/20 0.34
CYP11B1 P15538 1/20 0.34
PARP1 P09874 1/20 0.33
MAOA P21397 2/20 0.32
MAOB P27338 2/20 0.32
CYP1A2 P05177 1/20 0.32
PTGS2 P35354 1/20 0.31
DRD2 P14416 1/20 0.30
DRD4 P21917 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1577673 0.78 CYP11B2 (0.46) TRPA1CYP11B2CYP11B1MAOAMAOB
SCHEMBL1923169 0.74 TRPA1 (0.38) TRPA1CYP11B2CYP11B1PARP1MAOA
SCHEMBL5064106 0.74 CYP11B1 (0.43) TRPA1CYP11B2CYP11B1PARP1MAOA
SCHEMBL4309791 0.73 TRPA1 (0.36) TRPA1CYP11B2CYP11B1PARP1MAOA
SCHEMBL1681314 0.73 TRPA1 (0.36) TRPA1CYP11B2CYP11B1PARP1MAOA
SCHEMBL4313253 0.73 TRPA1 (0.36) TRPA1CYP11B2CYP11B1PARP1MAOA
SCHEMBL8681224 0.70 PARP1 (0.39) TRPA1CYP11B2CYP11B1PARP1MAOA
SCHEMBL4316325 0.70 AHR (0.36) CYP1A2
SCHEMBL283346 0.69 TRPA1 (0.50) TRPA1CYP11B2CYP11B1PARP1MAOA
SCHEMBL31586332 0.69 TRPA1 (0.50) TRPA1CYP11B2CYP11B1PARP1MAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2841433-A1 TETRAZOLINONE COMPOUNDS AND ITS USE Sumitomo Chemical Company Limited (JP) 2015-03-04 EP disclosed
EP-2841429-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES Sumitomo Chemical Company Limited (JP) 2015-03-04 EP disclosed
WO-2013162077-A1 TETRAZOLINONE COMPOUNDS AND ITS USE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-10-31 WO disclosed
WO-2013162072-A1 TETRAZOLINONE COMPOUNDS AND ITS USE AS PESTICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-10-31 WO disclosed
EP-2264009-A1 PYRIDYLAMINOACETIC ACID COMPOUND Ube Industries, Ltd. (JP) 2010-12-22 EP disclosed
WO-2008146063-A1 NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT6 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársagág (HU) 2008-12-04 WO disclosed