Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 3/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 2/20 | 0.32 |
| ▸ | MAOB | P27338 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29714904 | 0.76 | MAOA (0.42) | TRPA1MAOAMAOBCYP1A2CYP11B2 | |
| SCHEMBL29714906 | 0.76 | MAOA (0.42) | TRPA1MAOAMAOBCYP1A2CYP11B2 | |
| SCHEMBL1923169 | 0.74 | TRPA1 (0.38) | TRPA1PARP1MAOAMAOBCYP1A2 | |
| SCHEMBL4309791 | 0.73 | TRPA1 (0.36) | TRPA1PARP1MAOAMAOBCYP1A2 | |
| SCHEMBL3469802 | 0.73 | TRPA1 (0.36) | TRPA1PARP1MAOAMAOBCYP1A2 | |
| SCHEMBL5064106 | 0.70 | CYP11B1 (0.43) | TRPA1PARP1MAOAMAOBCYP11B2 | |
| SCHEMBL31586332 | 0.69 | TRPA1 (0.50) | TRPA1PARP1MAOAMAOBCYP1A2 | |
| SCHEMBL283346 | 0.69 | TRPA1 (0.50) | TRPA1PARP1MAOAMAOBCYP1A2 | |
| SCHEMBL6239530 | 0.68 | ACHE (0.39) | TRPA1PARP1MAOAMAOBPTGS2 | |
| SCHEMBL5022602 | 0.68 | TRPA1 (0.33) | TRPA1PARP1MAOAMAOBCYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2841433-A1 | TETRAZOLINONE COMPOUNDS AND ITS USE | Sumitomo Chemical Company Limited (JP) | 2015-03-04 | — | — | EP | disclosed |
| WO-2013162077-A1 | TETRAZOLINONE COMPOUNDS AND ITS USE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-10-31 | — | — | WO | disclosed |
| WO-2009136965-A1 | COMPOSITIONS AND METHODS COMPRISING CAPURAMYCIN ANALOGUES | SEQUELLA, INC. (US) | 2009-11-12 | — | — | WO | disclosed |
| WO-2008146063-A1 | NEW BENZOFURAN DERIVATIVES AS SELECTIVE 5HT6 RECEPTOR INHIBITORS AND PROCESS FOR THEIR PREPARATION | EGIS GYÓGYSZERGYÁR Nyilvánosan Müködö Részvénytársagág (HU) | 2008-12-04 | — | — | WO | disclosed |