Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN2 | P17706 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | PTPRS | Q13332 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 2/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 8/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.35 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CTSB | P07858 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | ACLY | P53396 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467062 | 0.90 | MMP13 (0.43) | PTPN2PTPN1STAT3PTPRSMMP13 | |
| SCHEMBL3467263 | 0.89 | PTPN2 (0.39) | PTPN2PTPN1STAT3PTPRSMMP13 | |
| SCHEMBL1855850 | 0.88 | STAT5B (0.40) | — | |
| SCHEMBL1860371 | 0.87 | STAT5B (0.41) | PTGER1 | |
| SCHEMBL3469959 | 0.85 | STAT3 (0.42) | PTPN2PTPN1STAT3PTPRSMMP13 | |
| SCHEMBL1861214 | 0.84 | ALDH1A1 (0.39) | — | |
| SCHEMBL3466770 | 0.83 | MMP13 (0.45) | PTPN2PTPN1STAT3PTPRSMMP13 | |
| SCHEMBL1855996 | 0.81 | STAT5B (0.36) | MMP13 | |
| SCHEMBL3467017 | 0.80 | MMP12 (0.57) | MMP13MMP12MCHR1ADAMTS4FFAR1 | |
| SCHEMBL1855155 | 0.80 | STAT5B (0.37) | MMP13CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |