Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 3/20 | 0.57 |
| ▸ | MMP13 | P45452 | 2/20 | 0.57 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.42 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | XDH | P47989 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | CTSG | P08311 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3467000 | 0.93 | MMP12 (0.51) | MMP12MMP13ADAMTS4MMP2MMP3 | |
| SCHEMBL3466543 | 0.90 | MMP12 (0.51) | MMP12MMP13MMEFAAHMMP2 | |
| SCHEMBL7932591 | 0.88 | MMP12 (0.63) | MMP12MMP13MMEFOLH1FAAH | |
| SCHEMBL7928277 | 0.87 | MMP12 (0.64) | MMP12MMP13MMEFOLH1FAAH | |
| SCHEMBL1860059 | 0.87 | MMP12 (0.53) | MMP12MMP13MMEMMP2MMP3 | |
| SCHEMBL1859451 | 0.86 | FFAR1 (0.44) | MMP12MMP13FOLH1MMP2MMP3 | |
| SCHEMBL3468279 | 0.85 | HCAR2 (0.47) | MMP12MMEFOLH1FFAR1FFAR4 | |
| SCHEMBL3466565 | 0.84 | GPR34 (0.54) | MMP12MMP13ADAMTS4FFAR1FFAR4 | |
| SCHEMBL3466501 | 0.84 | HCAR2 (0.52) | MMEMMP3 | |
| SCHEMBL3466739 | 0.84 | MMP2 (0.52) | MMP12MMEMMP2MMP3PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | claimed |
| WO-2010070076-A1 | ALKANOIC ACID DERIVATIVES AND THEIR THERAPEUTIC USE AS HDAC INHIBITORS | CRYSTAX PHARMACEUTICALS, S.L. (ES) | 2010-06-24 | — | — | WO | disclosed |