Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | GAA | P10253 | 5/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | GLA | P06280 | 2/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | CFTR | P13569 | 7/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264388 | 0.84 | KDM4E (0.47) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL2857865 | 0.84 | KDM4E (0.78) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL372600 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL31408659 | 0.80 | KDM4E (1.00) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL31716930 | 0.80 | KDM4E (0.76) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL267611 | 0.79 | KDM4E (0.55) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL4758833 | 0.78 | KDM4E (0.73) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL19554257 | 0.76 | GAA (0.59) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL5692887 | 0.76 | KDM4E (0.70) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL2900351 | 0.75 | KDM4E (0.82) | KDM4EALDH1A1GAAHSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147102-A1 | SYNTHETIC METHOD FOR 6,7-SUBSTITUENTS-4-ANILINE QUINAZOLINE | 翔真生物科技股份有限公司 (CN) | 2011-12-01 | — | — | WO | disclosed |
| US-20100267949-A1 | Method of Synthesizing 6,7-Substituted 4-Anilino Quinazoline | OMEGA MEDICAL TAIWAN LIMITED (TW) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267949-A1 | Method of Synthesizing 6,7-Substituted 4-Anilino Quinazoline | NQO2, ATIC, CYP3A7 | KDM4E 2145/4885ALDH1A1 878/4885GAA 927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.