SCHEMBL347011

SCHEMBL347011

COc1ccnc2sccc12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
RAB9A P51151 3/20 0.46
LMNA P02545 3/20 0.46
TNF P01375 2/20 0.44
NOD1 Q9Y239 2/20 0.44
NPC1 O15118 2/20 0.43
SMN1; SMN2 Q16637 2/20 0.42
GALR3 O60755 1/20 0.42
NR2F2 P24468 1/20 0.42
HTT P42858 1/20 0.42
MRGPRX1 Q96LB2 2/20 0.41
CYP1A2 P05177 1/20 0.41
CYP2C19 P33261 1/20 0.41
CHEK1 O14757 1/20 0.41
AURKA O14965 1/20 0.41
DAPK3 O43293 1/20 0.41
JAK2 O60674 1/20 0.41
MAP4K4 O95819 1/20 0.41
ABL1 P00519 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8374291 0.81 SMN1; SMN2 (0.44) MEN1KMT2ARAB9ALMNATNF
SCHEMBL7814831 0.79 MRGPRX1 (0.39) MEN1KMT2ARAB9ALMNATNF
SCHEMBL29365267 0.74 PDGFRB (0.42) HTTCYP1A2CYP2C19METPDGFRB
SCHEMBL8298164 0.74 PDGFRB (0.42) HTTCYP1A2CYP2C19METPDGFRB
SCHEMBL23937931 0.73 MEN1 (0.38) MEN1KMT2ARAB9ALMNATNF
SCHEMBL9542457 0.73 MMP10 (0.42) MEN1KMT2ATNFNOD1NPC1
SCHEMBL422299 0.72 CCR1 (0.48) MEN1KMT2ARAB9ALMNATNF
SCHEMBL23937935 0.71 RAB9A (0.71) MEN1KMT2ARAB9ALMNATNF
SCHEMBL8198195 0.71 DOT1L (0.40) PDGFRBDYRK1AIKBKB
SCHEMBL185654 0.70 CCR1 (0.50) MEN1KMT2ANPC1PDGFRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120016147-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-01-19 US disclosed
US-8048982-B2 Method for producing aromatic compound polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-11-01 US disclosed
EP-2241548-A1 Vanadium di-nuclear complex Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
EP-2241547-A1 Method for producing aromatic compound polymer Sumitomo Chemical Company, Limited (JP) 2010-10-20 EP disclosed
US-20090018309-A1 Method for Producing Aromatic Compound Polymer SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-01-15 US disclosed
EP-1767560-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER Sumitomo Chemical Company, Limited (JP) 2007-03-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090018309-A1 Method for Producing Aromatic Compound Polymer PAH, MAOA, AHR MEN1 4081/4885KMT2A 674/4885RAB9A 3951/4885
US-20120016147-A1 METHOD FOR PRODUCING AROMATIC COMPOUND POLYMER PAH, MAOA, AHR MEN1 4122/4885KMT2A 715/4885RAB9A 3968/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.