Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | SSTR5 | P35346 | 5/20 | 0.42 |
| ▸ | HTR1A | P08908 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.39 |
| ▸ | CCR1 | P32246 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2798126 | 0.94 | DRD3 (0.42) | DRD3SSTR5HTR1ADRD2ADRA1A | |
| SCHEMBL2798486 | 0.82 | HTR1A (0.43) | DRD3SSTR5HTR1ADRD2ADRA1A | |
| SCHEMBL2796586 | 0.81 | HTR4 (0.46) | DRD3SSTR5HTR1ADRD2ADRA1A | |
| SCHEMBL2794509 | 0.77 | CCR1 (0.48) | SSTR5HTR1ADRD2ADRA1AHTR4 | |
| SCHEMBL3470856 | 0.71 | CCR5 (0.42) | DRD3SSTR5HTR1ADRD2ADRA1A | |
| SCHEMBL2798788 | 0.70 | CCR5 (0.45) | HTR1ADRD2ADRA1ACHEK1CCR1 | |
| SCHEMBL13229942 | 0.69 | SSTR5 (0.46) | SSTR5HTR4 | |
| SCHEMBL3470860 | 0.69 | HTR4 (0.40) | DRD3SSTR5HTR1ADRD2ADRA1A | |
| SCHEMBL2792205 | 0.68 | SSTR5 (0.45) | SSTR5HTR4 | |
| SCHEMBL2798133 | 0.67 | ALDH1A1 (0.36) | HTR4CHEK1CCR1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010077915-A1 | NOVEL COMPOUNDS USEFUL AS CC CHEMOKINE RECEPTOR LIGANDS | FOREST LABORATORIES HOLDINGS LIMITED (BM) | 2010-07-08 | — | — | WO | disclosed |