Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.43 |
| ▸ | CDK9 | P50750 | 3/20 | 0.43 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.43 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.43 |
| ▸ | DYRK2 | Q92630 | 3/20 | 0.43 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | EED | O75530 | 1/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.41 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.41 |
| ▸ | TTK | P33981 | 3/20 | 0.39 |
| ▸ | ULK1 | O75385 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | MAPKAPK5 | Q8IW41 | 2/20 | 0.39 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.38 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5618954 | 0.82 | FLT3 (0.51) | ERN1DYRK3CCNT1CDK9CDK5 | |
| SCHEMBL11939102 | 0.81 | TTK (0.45) | ERN1EEDPTK6TTKMAPKAPK5 | |
| SCHEMBL3470478 | 0.77 | MAPKAPK5 (0.43) | EEDPTK6TTKMAPKAPK5ADORA3 | |
| SCHEMBL8240825 | 0.74 | AURKA (0.59) | CCNA2CDK2LCKPTK6TTK | |
| SCHEMBL5618947 | 0.73 | DYRK3 (0.44) | ERN1DYRK3CCNT1CDK9CDK5 | |
| SCHEMBL3470208 | 0.73 | FGFR2 (0.40) | EEDPTK6MAPKAPK5ADORA3SYK | |
| SCHEMBL3469690 | 0.73 | PRKD1 (0.44) | EEDTTKULK1MAPKAPK5ADORA3 | |
| SCHEMBL3468104 | 0.73 | FGFR2 (0.42) | PTK6TTKULK1MAPKAPK5ADORA3 | |
| SCHEMBL14537044 | 0.73 | AURKA (0.45) | PTK6TTKMAPKAPK5ADORA3SYK | |
| SCHEMBL8241606 | 0.73 | AURKA (0.58) | DYRK1APTK6MAPKAPK5SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | claimed |
| WO-2010069684-A1 | COMPOUNDS FOR TREATMENT OF DUCHENNE MUSCULAR DYSTROPHY | BIOMARIN IGA, LTD. (BS) | 2010-06-24 | — | — | WO | disclosed |