Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sebacic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.56 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.56 |
| ▸ | PPARG | P37231 | 7/20 | 0.54 |
| ▸ | PPARD | Q03181 | 7/20 | 0.54 |
| ▸ | PPARA | Q07869 | 7/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azelaic Acid SCHEMBL347853 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| Propylene Glycol SCHEMBL5035967 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| Octanedioate SCHEMBL28872523 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| Propylene Glycol SCHEMBL27855295 | 1.00 | TSHR (0.60) | TSHRLMNANFKB1PMP22GPR84 | |
| Sebacic Acid SCHEMBL29223184 | 0.98 | TSHR (0.57) | TSHRLMNANFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL346488 | 0.97 | LMNA (0.58) | TSHRLMNANFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL27922095 | 0.97 | LMNA (0.58) | TSHRLMNANFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL10936251 | 0.97 | LMNA (0.58) | TSHRLMNANFKB1PMP22GPR84 | |
| Adipic Acid SCHEMBL28436413 | 0.95 | LMNA (0.55) | TSHRLMNANFKB1PMP22GPR84 | |
| Sebacic Acid SCHEMBL20164089 | 0.93 | GPR84 (0.70) | TSHRLMNANFKB1PMP22GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 264 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119552540-A | Elastomer adhesion promoter and preparation method and brushing process thereof | 中船西安东仪科工集团有限公司 | 2025-03-04 | — | — | CN | claimed |
| CN-119432278-A | Modified epoxy resin conductive adhesive and preparation method thereof | 苏州市盛锦祥电子科技有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-119405122-A | Smash-resistant puncture-resistant special plastic boot | 安徽冠泓塑业有限公司 | 2025-02-11 | — | — | CN | claimed |
| US-12090243-B2 | Compositions comprising fluid gels for tissue separation | ALEO BME, INC. (US) | 2024-09-17 | — | — | US | claimed |
| CN-117965006-B | Preparation method of mildew-proof fresh-keeping bag | 广东骊虹包装有限公司 | 2024-06-07 | — | — | CN | claimed |
| CN-117965006-A | Preparation method of mildew-proof fresh-keeping bag | 广东骊虹包装有限公司 | 2024-05-03 | — | — | CN | claimed |
| EP-4313171-A1 | COMPOSITIONS COMPRISING FLUID GELS FOR TISSUE SEPARATION | Aleo BME, Inc. (US) | 2024-02-07 | — | — | EP | claimed |
| CN-115057867-B | Electrochromic compound, device, preparation method and application thereof | 吉林大学 | 2023-09-15 | — | — | CN | claimed |
| CN-114716763-B | Aging-resistant conductive polypropylene functional material and preparation method thereof | 华润化学材料科技股份有限公司 | 2023-07-25 | — | — | CN | claimed |
| CN-116271451-A | Shape-controllable nasal sinus sacculus catheter | 浙江桐轩医疗科技有限公司 | 2023-06-23 | — | — | CN | claimed |
| CN-101619147-B | Oil resistant butadiene-acrylonitrile rubber and preparation method thereof | SICHUAN STAR CABLE CO LTD | 2011-09-21 | — | — | CN | claimed |
| CN-101875746-A | Styrene series non-halogen flame retardant injection-grade wood plastic composite and preparation method thereof | KINGFA SCIENCE & TECHNOLOGY CO | 2010-11-03 | — | — | CN | claimed |
| CN-101864118-A | Styrene-based non-halogen flame-retardant injection-grade wood-plastic composite material and preparation method thereof | KINGFA SCIENCE & TECHNOLOGY CO | 2010-10-20 | — | — | CN | claimed |
| CN-101851362-A | Halogen-free flame-retardant polyolefin injection-grade wood-plastic composite and preparation method thereof | KINGFA SCIENCE & TECHNOLOGY CO | 2010-10-06 | — | — | CN | claimed |
| CN-101831112-A | Halogen-free flame-retardant type injection molding-class polyolefin wood plastic composite material and preparation method thereof | KINGFA SCIENCE & TECHNOLOGY CO | 2010-09-15 | — | — | CN | claimed |
| CN-101760037-A | Completely degraded plant powder modified thermoplastics composite material and preparation method thereof | KINGFA SCIENCE & TECHNOLOGY CO | 2010-06-30 | — | — | CN | claimed |
| CN-101747640-A | Modified plant powder for wood-plastics and preparation method and application thereof | KINGFA SCIENCE & TECHNOLOGY CO | 2010-06-23 | — | — | CN | claimed |
| CN-101747644-A | Plant powder modified thermoplastic wood-plastic composite and preparation method and application | KINGFA SCIENCE & TECHNOLOGY CO | 2010-06-23 | — | — | CN | claimed |
| CN-101619147-A | Oil resistant butadiene-acrylonitrile rubber and preparation method thereof | SICHUAN STAR CABLE CO LTD | 2010-01-06 | — | — | CN | claimed |
| EP-0606923-A2 | Melt processable biodegradable compositions and articles made therefrom | McNEIL-PPC, INC. (US) | 1994-07-20 | — | — | EP | claimed |