Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Sebacic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.70 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.70 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.70 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 7/20 | 0.48 |
| ▸ | PPARD | Q03181 | 7/20 | 0.48 |
| ▸ | PPARA | Q07869 | 7/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | FABP4 | P15090 | 2/20 | 0.48 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.48 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL6282986 | 0.98 | GPR84 (0.65) | GPR84FFAR4FFAR1CAMK2ATSHR | |
| Sebacic Acid SCHEMBL347212 | 0.93 | TSHR (0.60) | GPR84FFAR4FFAR1TSHRLMNA | |
| Propylene Glycol SCHEMBL27855295 | 0.93 | TSHR (0.60) | GPR84FFAR4FFAR1TSHRLMNA | |
| Azelaic Acid SCHEMBL347853 | 0.93 | TSHR (0.60) | GPR84FFAR4FFAR1TSHRLMNA | |
| Octanedioate SCHEMBL28872523 | 0.93 | TSHR (0.60) | GPR84FFAR4FFAR1TSHRLMNA | |
| Propylene Glycol SCHEMBL5035967 | 0.93 | TSHR (0.60) | GPR84FFAR4FFAR1TSHRLMNA | |
| Stearic Acid SCHEMBL6933117 | 0.92 | GPR84 (0.63) | GPR84FFAR4FFAR1TSHRLMNA | |
| Tridecan-1-Ol SCHEMBL6851195 | 0.92 | GPR84 (0.63) | GPR84FFAR4FFAR1TSHRLMNA | |
| Stearic Acid SCHEMBL28761911 | 0.92 | GPR84 (0.63) | GPR84FFAR4FFAR1TSHRLMNA | |
| Adipic Acid SCHEMBL902718 | 0.91 | GPR84 (0.54) | GPR84FFAR4FFAR1CAMK2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180143547-A1 | METHOD FOR PRODUCING TONER | CANON KABUSHIKI KAISHA (JP) | 2018-05-24 | — | — | US | disclosed |