SCHEMBL2295307

SCHEMBL2295307

CCOC(=O)C1(CC)CC1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
LMNA P02545 2/20 0.40
HSD17B10 Q99714 1/20 0.40
POLB P06746 1/20 0.40
OPRM1 P35372 6/20 0.39
ALOX15 P16050 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
SOAT1 P35610 1/20 0.39
ATM Q13315 1/20 0.38
MAPK1 P28482 1/20 0.38
OPRD1 P41143 3/20 0.38
OPRK1 P41145 3/20 0.38
SLC22A1 O15245 1/20 0.38
SLC6A4 P31645 1/20 0.38
ADRA1A P35348 1/20 0.38
KCNH2 Q12809 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17454 0.91 SMN1; SMN2 (0.40) ALDH1A1LMNAHSD17B10POLBOPRM1
SCHEMBL2289682 0.91 SMN1; SMN2 (0.44) ALDH1A1LMNAHSD17B10POLBOPRM1
SCHEMBL15114429 0.90 SMN1; SMN2 (0.37) ALDH1A1LMNAHSD17B10POLBOPRM1
SCHEMBL1142569 0.89 SMN1; SMN2 (0.39) ALDH1A1LMNAHSD17B10POLBOPRM1
SCHEMBL963382 0.86 OPRM1 (0.51) ALDH1A1LMNAHSD17B10POLBOPRM1
SCHEMBL20564117 0.86 TSHR (0.47) ALDH1A1LMNAPOLBALOX15GAA
SCHEMBL14212551 0.85 ALDH1A1 (0.41) ALDH1A1LMNAHSD17B10POLBOPRM1
Hydrochloric Acid SCHEMBL1282849 0.84 OPRM1 (0.50) ALDH1A1POLBOPRM1ALOX15SMN1; SMN2
SCHEMBL10203579 0.84 POLB (0.36) ALDH1A1LMNAPOLBOPRM1SMN1; SMN2
SCHEMBL12950188 0.84 OPRM1 (0.53) ALDH1A1LMNAPOLBOPRM1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113149968-B Compound serving as ketohexokinase inhibitor and application thereof 博济医药科技股份有限公司 2024-06-04 CN disclosed
US-20230150989-A1 HERBICIDAL MALONAMIDES BASF SE (DE) 2023-05-18 US disclosed
CN-106207261-B Electrolyte and battery 松下知识产权经营株式会社 2021-01-15 CN disclosed
CN-105392777-B Biaryl derivatives as GPR120 agonists 株式会社LG化学 2020-09-22 CN disclosed
US-10153512-B2 Electrolyte solution and battery PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2018-12-11 US disclosed
US-9630989-B2 Dipeptide analogs for treating conditions associated with amyloid fibril formation RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2017-04-25 US disclosed
US-20160351955-A1 ELECTROLYTE SOLUTION AND BATTERY PANASONIC INTELLECTUAL PROPERTY MANAGEMENT CO., LTD. (JP) 2016-12-01 US disclosed
EP-2604595-B1 TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY SHIONOGI & CO (JP) 2016-03-16 EP disclosed
US-9096645-B2 Dipeptide analogs for treating conditions associated with amyloid fibril formation RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) 2015-08-04 US disclosed
US-8372807-B2 Methods of modulating uric acid levels ARDEA BIOSCIENCES, INC. (US) 2013-02-12 US disclosed
US-7999136-B2 Amide compound and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-08-16 US disclosed
US-20100137445-A1 PLANT DISEASE CONTROL AGENT, AND PLANT DISEASE CONTROL METHOD SUMITOMO CHEMICAL COMPANY ,LIMITED 2010-06-03 US disclosed
US-20100137376-A1 AMIDE COMPOUND AND METHOD FOR CONTROLLING PLANT DISEASE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-03 US disclosed
EP-2179651-A1 PLANT DISEASE CONTROL AGENT, AND PLANT DISEASE CONTROL METHOD Sumitomo Chemical Company, Limited (JP) 2010-04-28 EP disclosed
EP-2174931-A1 AMIDE COMPOUND AND METHOD FOR CONTROLLING PLANT DISEASE USING THE SAME Sumitomo Chemical Company, Limited (JP) 2010-04-14 EP disclosed
US-20100069499-A1 AMIDE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-03-18 US disclosed
US-20100056640-A1 AMIDE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY LIMITED (JP) 2010-03-04 US disclosed
EP-2151431-A1 AMIDE COMPOUND AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2010-02-10 EP disclosed
EP-2143709-A1 AMIDE COMPOUND AND USE THEREOF Sumitomo Chemical Company, Limited (JP) 2010-01-13 EP disclosed
US-4273784-A PROSTAGLANDINS WITH CYCLOPROPANE RING IN 2,3 POSITION, OXYTOCICS, ANTISECRETORY, ANTICOAGULANTS, DECONGESTANTS SANDOZ LTD. (CH) 1981-06-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100056640-A1 AMIDE COMPOUND AND USE THEREOF NAT1, AGXT, HAX1 ALDH1A1 2983/4885LMNA 2672/4885HSD17B10 2289/4885
US-20100069499-A1 AMIDE COMPOUND AND USE THEREOF CBR1, CBR3, GBA1 ALDH1A1 2111/4885LMNA 3273/4885HSD17B10 2201/4885
US-20230150989-A1 HERBICIDAL MALONAMIDES DDT, DHRS9, CA9 ALDH1A1 475/4885LMNA 3455/4885HSD17B10 274/4885
US-20100137376-A1 AMIDE COMPOUND AND METHOD FOR CONTROLLING PLANT DISEASE USING THE SAME NAAA, NAT1, SAT1 ALDH1A1 3424/4885LMNA 2819/4885HSD17B10 2533/4885
US-20100137445-A1 PLANT DISEASE CONTROL AGENT, AND PLANT DISEASE CONTROL METHOD CBR3, CBR1, HDHD5 ALDH1A1 2677/4885LMNA 3993/4885HSD17B10 878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.