Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.51 |
| ▸ | HTR2A | P28223 | 1/20 | 0.51 |
| ▸ | SCN1A | P35498 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6602687 | 0.86 | ALDH1A1 (0.46) | KEAP1SMN1; SMN2HRH3MAPK1ALDH1A1 | |
| SCHEMBL5293921 | 0.82 | KEAP1 (0.58) | KEAP1SMN1; SMN2HRH3MAPK1ALDH1A1 | |
| SCHEMBL17980672 | 0.80 | KEAP1 (0.56) | KEAP1SMN1; SMN2HRH3MAPK1ALDH1A1 | |
| SCHEMBL27814848 | 0.79 | HRH3 (0.39) | KEAP1SMN1; SMN2HRH3MAPK1ALDH1A1 | |
| SCHEMBL23138463 | 0.78 | KEAP1 (0.54) | KEAP1SMN1; SMN2HRH3MAPK1ALDH1A1 | |
| SCHEMBL14793394 | 0.78 | KEAP1 (0.54) | KEAP1SMN1; SMN2HRH3MAPK1ALDH1A1 | |
| SCHEMBL15187726 | 0.78 | KEAP1 (0.54) | KEAP1SMN1; SMN2HRH3MAPK1ALDH1A1 | |
| SCHEMBL17982316 | 0.78 | KEAP1 (0.54) | KEAP1SMN1; SMN2HRH3MAPK1ALDH1A1 | |
| SCHEMBL8216914 | 0.78 | KEAP1 (0.54) | KEAP1SMN1; SMN2HRH3MAPK1ALDH1A1 | |
| SCHEMBL8216918 | 0.78 | KEAP1 (0.59) | KEAP1SMN1; SMN2HRH3MAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100267949-A1 | Method of Synthesizing 6,7-Substituted 4-Anilino Quinazoline | OMEGA MEDICAL TAIWAN LIMITED (TW) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267949-A1 | Method of Synthesizing 6,7-Substituted 4-Anilino Quinazoline | NQO2, ATIC, CYP3A7 | KEAP1 666/4885SMN1; SMN2 3906/4885HRH3 2490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.