Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | CCKBR | P32239 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14866024 | 0.86 | MET (0.48) | METCYP1A2CYP11B1CYP11B2CCKBR | |
| SCHEMBL3306023 | 0.86 | MEN1 (0.45) | METCYP1A2CYP11B1CYP11B2MEN1 | |
| SCHEMBL3306832 | 0.84 | MET (0.47) | METCYP1A2CYP11B1CYP11B2MAPT | |
| SCHEMBL3301564 | 0.82 | MET (0.47) | METCYP1A2CYP11B1CYP11B2CCKBR | |
| SCHEMBL3470514 | 0.81 | MET (0.46) | METCYP1A2CYP11B1CYP11B2CCKBR | |
| SCHEMBL4477991 | 0.79 | ATAD2 (0.45) | METCCKBRMAPT | |
| SCHEMBL3308636 | 0.79 | MET (0.45) | METCYP1A2CYP11B1CYP11B2MAPT | |
| SCHEMBL3310478 | 0.78 | MAPT (0.54) | METCCKBRMAPTALDH1A1 | |
| SCHEMBL16435149 | 0.75 | CYP11B1 (0.38) | CYP1A2CYP11B1CYP11B2ALDH1A1 | |
| SCHEMBL14866213 | 0.75 | CCKBR (0.48) | METCCKBRMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010074807-A1 | 3, 4-DIHYDROQUINOLIN-2 ( 1H ) -ONE DERIVATIVES AS SODIUM CHANNEL MODULATORS | GILEAD PALO ALTO, INC. (US) | 2010-07-01 | — | — | WO | disclosed |