Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | DPP4 | P27487 | 5/20 | 0.43 |
| ▸ | FDPS | P14324 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | GALR2 | O43603 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3471737 | 0.88 | KMT2A (0.48) | KMT2AALDH1A1GAAMAPTLMNA | |
| SCHEMBL3471175 | 0.81 | KMT2A (0.56) | KMT2AALDH1A1GAAMAPTDPP4 | |
| SCHEMBL2333730 | 0.76 | HTT (0.59) | KMT2AALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL2900687 | 0.76 | KMT2A (0.65) | KMT2AALDH1A1GAAMAPTDPP4 | |
| SCHEMBL5500527 | 0.76 | HTT (0.53) | KMT2AALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL13168044 | 0.75 | PKM (0.50) | KMT2AALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL8263297 | 0.75 | MEN1 (0.55) | KMT2AALDH1A1MAPTDPP4LMNA | |
| SCHEMBL10118722 | 0.74 | PKM (0.49) | KMT2AALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL7719088 | 0.74 | PKM (0.49) | KMT2AALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL18417238 | 0.73 | KMT2A (0.54) | KMT2AALDH1A1GAADPP4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102746242-A | Synthesis method of 6, 7-substituent-4-aniline quinazoline | OMEGA CO LTD | 2012-10-24 | — | — | CN | disclosed |
| CN-101863844-B | Synthesis method of 6, 7-substituent-4-aniline quinazoline | XIANGZHEN BIOLOGY TECHNOLOGY CO LTD | 2012-10-03 | — | — | CN | disclosed |
| US-20100267949-A1 | Method of Synthesizing 6,7-Substituted 4-Anilino Quinazoline | OMEGA MEDICAL TAIWAN LIMITED (TW) | 2010-10-21 | — | — | US | disclosed |
| CN-101863844-A | Synthesis method of 6, 7-substituent-4-aniline quinazoline | XIANGZHEN BIOLOGY TECHNOLOGY CO LTD | 2010-10-20 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267949-A1 | Method of Synthesizing 6,7-Substituted 4-Anilino Quinazoline | NQO2, ATIC, CYP3A7 | KMT2A 2686/4885ALDH1A1 878/4885GAA 927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.