Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.41 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.41 |
| ▸ | OXTR | P30559 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 4/20 | 0.39 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.37 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.37 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | MME | P08473 | 1/20 | 0.35 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 2/20 | 0.33 |
| ▸ | CTSB | P07858 | 2/20 | 0.33 |
| ▸ | CTSK | P43235 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3473583 | 1.00 | ITGB1 (0.41) | ITGB1ITGA4AVPR1AOXTRFFAR1 | |
| SCHEMBL6016794 | 0.91 | ITGB1 (0.36) | ITGB1ITGA4AVPR1AOXTRFFAR1 | |
| SCHEMBL6016793 | 0.91 | ITGB1 (0.36) | ITGB1ITGA4AVPR1AOXTRFFAR1 | |
| SCHEMBL3473572 | 0.87 | FFAR1 (0.46) | ITGB1ITGA4AVPR1AOXTRFFAR1 | |
| SCHEMBL3473577 | 0.87 | FFAR1 (0.46) | ITGB1ITGA4AVPR1AOXTRFFAR1 | |
| SCHEMBL2140 | 0.84 | AGTR1 (0.54) | FFAR1AKR1B1AGTR1LTB4R2ABCB11 | |
| SCHEMBL29378073 | 0.84 | AGTR1 (0.54) | FFAR1AKR1B1AGTR1LTB4R2ABCB11 | |
| SCHEMBL1809623 | 0.84 | AGTR1 (0.54) | FFAR1AKR1B1AGTR1LTB4R2ABCB11 | |
| SCHEMBL8360853 | 0.82 | ITGB1 (0.45) | ITGB1ITGA4AVPR1AOXTRFFAR1 | |
| SCHEMBL2651 | 0.81 | ALDH1A1 (0.52) | ITGB1ITGA4AVPR1AOXTRFFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100048654-A1 | USE OF VALSARTAN OR ITS METABOLITE TO IN HIBIT PLATELET AGGREGATION | NOVARTIS PHARMACEUTICALS CORPORATION | 2010-02-25 | — | — | US | disclosed |
| US-20100048654-A1 | USE OF VALSARTAN OR ITS METABOLITE TO IN HIBIT PLATELET AGGREGATION | NOVARTIS PHARMACEUTICALS CORPORATION | 2010-02-25 | — | — | US | disclosed |
| US-20100048654-A1 | USE OF VALSARTAN OR ITS METABOLITE TO IN HIBIT PLATELET AGGREGATION | NOVARTIS PHARMACEUTICALS CORPORATION | 2010-02-25 | — | — | US | disclosed |
| US-20050197372-A1 | Use of valsartan or its metabolite to inhibit platelet aggregation | MALININ ALEX (US) | 2005-09-08 | — | — | US | disclosed |
| EP-1505965-A1 | USE OF VALSARTAN OT ITS METABOLITE TO INHIBIT PLATELET AGGREGATION | Novartis AG (CH) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003094915-A1 | USE OF VALSARTAN OT ITS METABOLITE TO INHIBIT PLATELET AGGREGATION | NOVARTIS AG (CH) | 2003-11-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100048654-A1 | USE OF VALSARTAN OR ITS METABOLITE TO IN HIBIT PLATELET AGGREGATION | PDGFRA, PLAT, PTAFR | ITGB1 1373/4885ITGA4 635/4885AVPR1A 362/4885 |
| US-20050197372-A1 | Use of valsartan or its metabolite to inhibit platelet aggregation | PTAFR, PDGFRA, ACE | ITGB1 1361/4885ITGA4 657/4885AVPR1A 193/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.