Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 1/20 | 0.36 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.36 |
| ▸ | AGTR1 | P30556 | 3/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | OXTR | P30559 | 1/20 | 0.33 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | GP6 | Q9HCN6 | 1/20 | 0.32 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.32 |
| ▸ | CTSL | P07711 | 4/20 | 0.32 |
| ▸ | CTSB | P07858 | 4/20 | 0.32 |
| ▸ | CTSK | P43235 | 4/20 | 0.32 |
| ▸ | CTSS | P25774 | 4/20 | 0.32 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016794 | 1.00 | ITGB1 (0.36) | ITGB1ITGA4AGTR1PTGDR2OXTR | |
| SCHEMBL3473579 | 0.91 | ITGB1 (0.41) | ITGB1ITGA4AGTR1OXTRAVPR1A | |
| SCHEMBL3473583 | 0.91 | ITGB1 (0.41) | ITGB1ITGA4AGTR1OXTRAVPR1A | |
| SCHEMBL2441623 | 0.84 | AGTR1 (0.47) | AGTR1FFAR1AKR1B1ABCB11GP6 | |
| SCHEMBL2210 | 0.81 | CTSS (0.39) | FFAR1AKR1B1CTSLCTSBCTSK | |
| SCHEMBL3473572 | 0.78 | FFAR1 (0.46) | ITGB1ITGA4AGTR1OXTRAVPR1A | |
| SCHEMBL3473577 | 0.78 | FFAR1 (0.46) | ITGB1ITGA4AGTR1OXTRAVPR1A | |
| SCHEMBL8476139 | 0.76 | AGTR1 (0.57) | AGTR1ABCB11GP6LTB4R2 | |
| SCHEMBL27753418 | 0.76 | AGTR1 (0.57) | AGTR1ABCB11GP6LTB4R2 | |
| SCHEMBL8476142 | 0.76 | AGTR1 (0.57) | AGTR1ABCB11GP6LTB4R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1505965-B1 | USE OF THE METABOLITE OF VALSARTAN TO INHIBIT PLATELET AGGREGATION | NOVARTIS AG (CH) | 2006-08-02 | — | — | EP | disclosed |
| EP-1505965-A1 | USE OF VALSARTAN OT ITS METABOLITE TO INHIBIT PLATELET AGGREGATION | Novartis AG (CH) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003094915-A1 | USE OF VALSARTAN OT ITS METABOLITE TO INHIBIT PLATELET AGGREGATION | NOVARTIS AG (CH) | 2003-11-20 | — | — | WO | disclosed |