SCHEMBL3473753

SCHEMBL3473753

O=C1OC(=O)c2c1cccc2-c1ccccc1S(=O)(=O)O

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
PGAM1 P18669 1/20 0.41
NFKB1 P19838 2/20 0.39
KDM4A O75164 1/20 0.39
USP2 O75604 1/20 0.39
NSD2 O96028 1/20 0.39
ALPL P05186 1/20 0.39
PLCG1 P19174 1/20 0.39
TNNI3 P19429 1/20 0.39
TNNT2 P45379 1/20 0.39
MMP14 P50281 1/20 0.39
CASP6 P55212 1/20 0.39
TNNC1 P63316 1/20 0.39
KDM4C Q9H3R0 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
TYMS P04818 2/20 0.37
STAT3 P40763 1/20 0.37
TTR P02766 2/20 0.36
ALDH1A1 P00352 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2281726 0.87 ALOX15 (0.43) ALOX15TDP1PGAM1NFKB1KDM4A
SCHEMBL458284 0.79 SMN1; SMN2 (0.48) PGAM1NFKB1KDM4AUSP2NSD2
SCHEMBL31548711 0.79 TDP1 (0.60) ALOX15TDP1PLCG1L3MBTL1TYMS
SCHEMBL2087097 0.79 TDP1 (0.60) ALOX15TDP1PLCG1L3MBTL1TYMS
SCHEMBL28837581 0.77 SMN1; SMN2 (0.46) PGAM1NFKB1KDM4AUSP2NSD2
SCHEMBL766110 0.76 ALOX15 (0.46) ALOX15TDP1PLCG1TYMSSTAT3
SCHEMBL2592300 0.75 PGAM1 (0.44) PGAM1NFKB1KDM4AUSP2NSD2
SCHEMBL13786941 0.75 ALOX15 (0.37) ALOX15TDP1PGAM1NFKB1KDM4A
SCHEMBL24631331 0.75 TTR (0.47) ALOX15TDP1PGAM1STAT3TTR
SCHEMBL9763220 0.74 MAPT (0.52) PGAM1NFKB1KDM4AUSP2NSD2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8354493-B2 Polyamic acid composition, polyimide endless belt, belt supporting member, fixing member and image formation device FUJI XEROX CO., LTD. (JP) 2013-01-15 US disclosed
US-20100233488-A1 POLYAMIC ACID COMPOSITION, POLYIMIDE ENDLESS BELT, BELT SUPPORTING MEMBER, FIXING MEMBER AND IMAGE FORMATION DEVICE FUJI XEROX CO., LTD. (JP) 2010-09-16 US disclosed