Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701066 | 0.82 | ALDH1A1 (0.53) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6438319 | 0.78 | LTA4H (0.54) | LTA4HCA12CA1CA2CA7 | |
| SCHEMBL6182907 | 0.78 | SMN1; SMN2 (0.52) | LTA4HCA12CA1CA2CA7 | |
| SCHEMBL166536 | 0.76 | CA1 (0.79) | LTA4HCA12CA1CA2CA7 | |
| SCHEMBL11580995 | 0.76 | CA1 (0.79) | LTA4HCA12CA1CA2CA7 | |
| SCHEMBL83811 | 0.76 | CA1 (0.79) | LTA4HCA12CA1CA2CA7 | |
| SCHEMBL5343776 | 0.76 | ALDH1A1 (0.68) | LTA4HCA12CA1CA2CA7 | |
| SCHEMBL5837204 | 0.75 | LTA4H (0.61) | LTA4HCA12CA1CA2CA7 | |
| SCHEMBL3474051 | 0.75 | POLB (0.46) | LTA4HCA12CA1CA2CA7 | |
| Phosphine SCHEMBL22689591 | 0.74 | LTA4H (0.74) | LTA4HCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8420235-B2 | Emissive diaryl acetylenes | NITTO DENKO CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8420235-B2 | Emissive diaryl acetylenes | NITTO DENKO CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8420235-B2 | Emissive diaryl acetylenes | NITTO DENKO CORPORATION (JP) | 2013-04-16 | — | — | US | disclosed |
| US-8323805-B2 | Emissive aryl-heteroaryl acetylenes | NITTO DENKO CORPORATION (JP) | 2012-12-04 | — | — | US | disclosed |
| US-8323805-B2 | Emissive aryl-heteroaryl acetylenes | NITTO DENKO CORPORATION (JP) | 2012-12-04 | — | — | US | disclosed |
| US-8323805-B2 | Emissive aryl-heteroaryl acetylenes | NITTO DENKO CORPORATION (JP) | 2012-12-04 | — | — | US | disclosed |
| US-20100308310-A1 | EMISSIVE ARYL-HETEROARYL ACETYLENES | Nitto Denko Corporaton (JP) | 2010-12-09 | — | — | US | disclosed |
| US-20100308310-A1 | EMISSIVE ARYL-HETEROARYL ACETYLENES | Nitto Denko Corporaton (JP) | 2010-12-09 | — | — | US | disclosed |
| US-20100308310-A1 | EMISSIVE ARYL-HETEROARYL ACETYLENES | Nitto Denko Corporaton (JP) | 2010-12-09 | — | — | US | disclosed |
| WO-2010141758-A1 | EMISSIVE ARYL-HETEROARYL ACETYLENES | NITTO DENKO CORPORATION (JP) | 2010-12-09 | — | — | WO | disclosed |
| WO-2010141758-A1 | EMISSIVE ARYL-HETEROARYL ACETYLENES | NITTO DENKO CORPORATION (JP) | 2010-12-09 | — | — | WO | disclosed |
| US-20100308716-A1 | EMISSIVE DIARYL ACETYLENES | NITTO DENKO CORPORATION (JP) | 2010-12-09 | — | — | US | disclosed |
| US-20100308716-A1 | EMISSIVE DIARYL ACETYLENES | NITTO DENKO CORPORATION (JP) | 2010-12-09 | — | — | US | disclosed |
| US-20100308716-A1 | EMISSIVE DIARYL ACETYLENES | NITTO DENKO CORPORATION (JP) | 2010-12-09 | — | — | US | disclosed |
| WO-2010141754-A1 | EMISSIVE DIARYL ACETYLENES | NITTO DENKO CORPORATION (JP) | 2010-12-09 | — | — | WO | disclosed |
| WO-2010141754-A1 | EMISSIVE DIARYL ACETYLENES | NITTO DENKO CORPORATION (JP) | 2010-12-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100308310-A1 | EMISSIVE ARYL-HETEROARYL ACETYLENES | NAT1, AADAC, CORO1C | LTA4H 734/4885CA12 3444/4885CA1 4133/4885 |
| US-20100308716-A1 | EMISSIVE DIARYL ACETYLENES | B3GNT2, GSTO1, NAT1 | LTA4H 255/4885CA12 978/4885CA1 1463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.