Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.36 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PIM1 | P11309 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8777923 | 0.77 | TSHR (0.46) | ALDH1A1TSHRAOC3TAAR1NR1H2 | |
| SCHEMBL3069583 | 0.76 | ESR1 (0.37) | ALDH1A1TSHRAOC3NPC1RAB9A | |
| SCHEMBL27884955 | 0.72 | ALDH1A1 (0.41) | ALDH1A1TSHRAOC3TAAR1KMT2A | |
| SCHEMBL28949883 | 0.71 | ALDH1A1 (0.40) | ALDH1A1TSHRAOC3TAAR1NR1H2 | |
| SCHEMBL6264576 | 0.70 | NR1H2 (0.42) | ALDH1A1TSHRNR1H2NR1H3TP53 | |
| SCHEMBL3839629 | 0.70 | NR1H2 (0.59) | ALDH1A1TSHRNR1H2NR1H3TP53 | |
| SCHEMBL987145 | 0.69 | CALM1 (0.43) | ALDH1A1TSHRAOC3TAAR1NR1H2 | |
| Hydrochloric Acid SCHEMBL8045525 | 0.69 | NR1H2 (0.58) | ALDH1A1TSHRNR1H2NR1H3TP53 | |
| Hydrochloric Acid SCHEMBL821914 | 0.68 | ALDH1A1 (0.37) | ALDH1A1TSHRAOC3TAAR1NR1H2 | |
| Bromide SCHEMBL821352 | 0.68 | ALDH1A1 (0.37) | ALDH1A1TSHRAOC3TAAR1NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100301494-A1 | RE-ESTABLISHING A HYDROPHOBIC SURFACE OF SENSITIVE LOW-K DIELECTRICS IN MICROSTRUCTURE DEVICES | GLOBALFOUNDRIES U.S. INC. | 2010-12-02 | — | — | US | disclosed |