Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 8/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.48 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.47 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.47 |
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | GALR2 | O43603 | 1/20 | 0.45 |
| ▸ | GALR1 | P47211 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3477307 | 0.82 | FAAH (0.66) | FAAHHDAC6PIK3CAMAPT | |
| SCHEMBL3477409 | 0.81 | FAAH (0.71) | FAAHHDAC6PIK3CANPC1MAPT | |
| SCHEMBL3475819 | 0.81 | FAAH (0.65) | FAAHHDAC6PIK3CANPC1RAB9A | |
| SCHEMBL3477061 | 0.80 | FAAH (0.58) | FAAHHDAC6PIK3CAMAPT | |
| SCHEMBL3476787 | 0.80 | FAAH (0.72) | FAAHHDAC6PIK3CASSTR5SMN1; SMN2 | |
| SCHEMBL13543032 | 0.80 | SSTR5 (0.54) | FAAHHDAC6PIK3CASSTR5FBP1 | |
| Bromide SCHEMBL3568591 | 0.79 | SSTR5 (0.53) | FAAHHDAC6PIK3CASSTR5FBP1 | |
| SCHEMBL3475830 | 0.78 | FAAH (0.64) | FAAHHDAC6PIK3CASSTR5 | |
| SCHEMBL3477428 | 0.78 | FAAH (0.64) | FAAHHDAC6PIK3CA | |
| SCHEMBL13436763 | 0.78 | FAAH (0.76) | FAAHHDAC6PIK3CASSTR5MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |
| WO-2010039186-A2 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2010-04-08 | — | — | WO | disclosed |