Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | PNMT | P11086 | 2/20 | 0.50 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 3/20 | 0.47 |
| ▸ | HTR3B | O95264 | 3/20 | 0.47 |
| ▸ | HTR3A | P46098 | 3/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 3/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 3/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | AGXT | P21549 | 2/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28477012 | 0.86 | PNMT (0.48) | MAOBPNMTTAAR1HTR3EHTR3B | |
| SCHEMBL3693386 | 0.85 | ATM (0.39) | MAOBTAAR1 | |
| SCHEMBL73643 | 0.83 | PNMT (0.54) | PNMTTAAR1HTR3EHTR3BHTR3A | |
| Ammonia Solution, Strong SCHEMBL27962080 | 0.82 | PNMT (0.52) | PNMTTAAR1HTR3EHTR3BHTR3A | |
| SCHEMBL5925967 | 0.81 | PNMT (0.47) | PNMTTAAR1HTR3EHTR3BHTR3A | |
| SCHEMBL11667803 | 0.80 | RIPK1 (0.48) | PNMTTAAR1HTR3EHTR3BHTR3A | |
| SCHEMBL5222434 | 0.80 | SLC6A2 (0.59) | PNMTTAAR1HTR3EHTR3BHTR3A | |
| SCHEMBL7109269 | 0.80 | PNMT (0.50) | PNMTTAAR1HTR3EHTR3BHTR3A | |
| SCHEMBL3476733 | 0.79 | RIPK1 (0.54) | MAOBPNMTTAAR1HTR3EHTR3B | |
| SCHEMBL11659390 | 0.79 | HTR3E (0.44) | MAOBPNMTTAAR1HTR3EHTR3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230150933-A1 | BROAD SPECTRUM ANTIVIRALS AGAINST CORONAVIRUS | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2023-05-18 | — | — | US | disclosed |
| US-20230150933-A1 | BROAD SPECTRUM ANTIVIRALS AGAINST CORONAVIRUS | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2023-05-18 | — | — | US | disclosed |
| WO-2021202460-A1 | BROAD SPECTRUM ANTIVIRALS AGAINST CORONAVIRUS | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2021-10-07 | — | — | WO | disclosed |
| US-7253198-B2 | Hydroxyethylamine derivatives for the treatment of Alzheimer's disease | GLAXO GROUP LIMITED (GB) | 2007-08-07 | — | — | US | disclosed |
| US-7253198-B2 | Hydroxyethylamine derivatives for the treatment of Alzheimer's disease | GLAXO GROUP LIMITED (GB) | 2007-08-07 | — | — | US | disclosed |
| WO-2004050619-A1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LIMITED (GB) | 2004-06-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230150933-A1 | BROAD SPECTRUM ANTIVIRALS AGAINST CORONAVIRUS | SARS1, ZC3HAV1, POLL | MAOB 2122/4885PNMT 1478/4885TAAR1 3374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.