Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 4/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 3/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.30 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.30 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.30 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.30 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5180297 | 0.74 | SIGMAR1 (0.40) | — | |
| SCHEMBL3482739 | 0.73 | TP53 (0.42) | TRPA1 | |
| SCHEMBL16610487 | 0.73 | — | — | |
| SCHEMBL27725786 | 0.72 | TP53 (0.39) | — | |
| SCHEMBL15310711 | 0.71 | — | — | |
| SCHEMBL1149239 | 0.70 | MIF (0.66) | MIFMAOAMAOBNAAAKEAP1 | |
| SCHEMBL7937549 | 0.70 | ALDH1A1 (0.37) | — | |
| Diphenylmethane SCHEMBL28176599 | 0.69 | MIF (0.50) | MIFMAOAMAOBNAAAKEAP1 | |
| SCHEMBL425325 | 0.69 | MIF (0.67) | MIFMAOAMAOBNAAAKEAP1 | |
| SCHEMBL11419140 | 0.68 | MIF (0.58) | MIFMAOAMAOBNAAATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112142945-B | High-stability silyl-terminated polymer resin and preparation method thereof | 万华化学集团股份有限公司 | 2022-07-12 | — | — | CN | claimed |
| EP-2069415-B1 | PROCESS FOR PREPARING A CURABLE SILYLATED POLYURETHANE RESIN | MOMENTIVE PERFORMANCE MAT INC (US) | 2021-04-21 | — | — | EP | claimed |
| CN-107406570-B | Silylated polyurethanes, their preparation and use | 汉高股份有限及两合公司 | 2021-02-19 | — | — | CN | claimed |
| CN-112142945-A | High-stability silyl-terminated polymer resin and preparation method thereof | 万华化学集团股份有限公司 | 2020-12-29 | — | — | CN | claimed |
| US-20190031812-A1 | Silylated Polyurethanes, Their Preparation and Use | HENKEL AG & CO. KGAA (DE) | 2019-01-31 | — | — | US | claimed |
| US-10118984-B2 | Silylated polyurethanes, their preparation and use | HENKEL AG & CO. KGAA (DE) | 2018-11-06 | — | — | US | claimed |
| US-20170362371-A1 | Silylated Polyurethanes, Their Preparation and Use | HENKEL AG & CO. KGAA (DE) | 2017-12-21 | — | — | US | claimed |
| EP-3067375-B1 | SILYLATED POLYURETHANES, THEIR PREPARATION AND USE | HENKEL AG & CO KGAA (DE) | 2017-08-30 | — | — | EP | claimed |
| WO-2016142416-A1 | SILYLATED POLYURETHANES, THEIR PREPARATION AND USE | HENKEL AG & CO. KGAA (DE) | 2016-09-15 | — | — | WO | claimed |
| EP-3067375-A1 | SILYLATED POLYURETHANES, THEIR PREPARATION AND USE | Henkel AG & Co. KGaA (DE) | 2016-09-14 | — | — | EP | claimed |
| EP-2069415-A1 | PROCESS FOR PREPARING A CURABLE SILYLATED POLYURETHANE RESIN | Momentive Performance Materials Inc. (US) | 2009-06-17 | — | — | EP | claimed |
| EP-1937697-A2 | METHOD FOR PRODUCTION OF ISOCYANATOSILANES | Momentive Performance Materials Inc. (US) | 2008-07-02 | — | — | EP | claimed |
| CN-101189246-A | Process for the production of isocyanatosilane and silylisocyanurate | MOMENTIVE PERFORMANCE MAT INC (US) | 2008-05-28 | — | — | CN | claimed |
| WO-2008036364-A1 | PROCESS FOR PREPARING A CURABLE SILYLATED POLYURETHANE RESIN | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2008-03-27 | — | — | WO | claimed |
| US-20080076899-A1 | Process for preparing a curable silylated polyurethane resin | GENERAL ELECTRIC COMPANY (US) | 2008-03-27 | — | — | US | claimed |
| EP-1885731-A1 | PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE | Momentive Performance Materials Inc. (US) | 2008-02-13 | — | — | EP | claimed |
| WO-2007037817-A2 | METHOD FOR PRODUCTION OF ISOCYANATOSILANES | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2007-04-05 | — | — | WO | claimed |
| WO-2006132799-A1 | PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2006-12-14 | — | — | WO | claimed |
| US-20060276644-A1 | Process for the production of isocyanatosilane and silylisocyanurate | GENERAL ELECTRIC COMPANY | 2006-12-07 | — | — | US | claimed |
| US-7060849-B1 | Method for production of isocyanatosilanes | GENERAL ELECTRIC COMPANY (US) | 2006-06-13 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276644-A1 | Process for the production of isocyanatosilane and silylisocyanurate | SI, TST, PCMT1 | MIF 640/4885MAOA 3925/4885MAOB 3901/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.