SCHEMBL3477291

SCHEMBL3477291

CCC(n1c(=O)n(C(CC)[Si](C)(OC)c2ccccc2)c(=O)n(C(CC)[Si](C)(OC)c2ccccc2)c1=O)[Si](C)(OC)c1ccccc1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.33
SLC6A2 P23975 3/20 0.31
CYP2C9 P11712 4/20 0.31
FAAH O00519 1/20 0.31
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4603203 0.71
SCHEMBL14841766 0.67 ESR1 (0.37) L3MBTL1CYP2C9FAAH
SCHEMBL29033096 0.65 ESR1 (0.35)
SCHEMBL30502381 0.63 LMNA (0.32)
SCHEMBL30502380 0.63 LMNA (0.32)
SCHEMBL20583812 0.63 LMNA (0.32)
SCHEMBL6144719 0.62 LMNA (0.34)
SCHEMBL1314424 0.62 LMNA (0.34) SLC6A2SLC6A4
SCHEMBL6143761 0.62 LMNA (0.34)
SCHEMBL837628 0.61 ESR1 (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7825243-B2 Process for the production of isocyanatosilane and silylisocyanurate MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-11-02 US claimed
EP-1885731-B1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE MOMENTIVE PERFORMANCE MAT INC (US) 2009-11-11 EP claimed
EP-1937697-A2 METHOD FOR PRODUCTION OF ISOCYANATOSILANES Momentive Performance Materials Inc. (US) 2008-07-02 EP claimed
EP-1885731-A1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE Momentive Performance Materials Inc. (US) 2008-02-13 EP claimed
WO-2007037817-A2 METHOD FOR PRODUCTION OF ISOCYANATOSILANES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-04-05 WO claimed
WO-2006132799-A1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2006-12-14 WO claimed
US-20060276644-A1 Process for the production of isocyanatosilane and silylisocyanurate GENERAL ELECTRIC COMPANY 2006-12-07 US claimed
US-7060849-B1 Method for production of isocyanatosilanes GENERAL ELECTRIC COMPANY (US) 2006-06-13 US claimed
EP-2768885-B1 MULTI-COMPONENT ROOM-TEMPERATURE-CURABLE SILICONE ELASTOMER COMPOSITION DOW CORNING TORAY CO LTD (JP) 2018-05-23 EP disclosed
US-20140288246-A1 Multi-Component Room-Temperature-Curable Silicone Elastomer Composition DOW CORNING TORAY CO., LTD. (JP) 2014-09-25 US disclosed
US-7825243-B2 Process for the production of isocyanatosilane and silylisocyanurate MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-11-02 US disclosed
EP-1885731-B1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE MOMENTIVE PERFORMANCE MAT INC (US) 2009-11-11 EP disclosed
EP-1885731-A1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE Momentive Performance Materials Inc. (US) 2008-02-13 EP disclosed
WO-2006132799-A1 PROCESS FOR THE PRODUCTION OF ISOCYANATOSILANE AND SILYLISOCYANURATE MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2006-12-14 WO disclosed
US-20060276644-A1 Process for the production of isocyanatosilane and silylisocyanurate GENERAL ELECTRIC COMPANY 2006-12-07 US disclosed
US-5905150-A HEATING IN PRESENCE OF PHASE TRANSFER AGENT GENERAL ELECTRIC COMPANY (US) 1999-05-18 US disclosed
EP-0900801-A1 Process for preparing organosilanes GENERAL ELECTRIC COMPANY (US) 1999-03-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060276644-A1 Process for the production of isocyanatosilane and silylisocyanurate SI, TST, PCMT1 L3MBTL1 3138/4885SLC6A2 4149/4885CYP2C9 344/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.