SCHEMBL3477372

SCHEMBL3477372

CCC(N=C=O)c1ccccc1CCO[SiH3]

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MIF P14174 1/20 0.33
GABRA1 P14867 1/20 0.32
GABRB2 P47870 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL330826 0.78 MIF (0.44) MIFGABRA1GABRB2
SCHEMBL14841768 0.72 GABRA1 (0.38) GABRA1GABRB2
SCHEMBL5607730 0.71 MIF (0.39) MIFGABRA1GABRB2
SCHEMBL5325552 0.70 MIF (0.35) MIF
SCHEMBL11431709 0.69 CYP2C9 (0.42) MIF
SCHEMBL4779751 0.69 MIF (0.34) MIF
SCHEMBL7268679 0.69 MIF (0.32) MIF
SCHEMBL22574607 0.68 MIF (0.33) MIF
SCHEMBL23527558 0.67 CYP3A4 (0.35) MIFGABRA1GABRB2
SCHEMBL21259588 0.67 CYP3A4 (0.35) MIFGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1937697-B1 METHOD FOR PRODUCTION OF ISOCYANATOSILANES MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-16 EP claimed
US-7825243-B2 Process for the production of isocyanatosilane and silylisocyanurate MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2010-11-02 US claimed
EP-1937697-A2 METHOD FOR PRODUCTION OF ISOCYANATOSILANES Momentive Performance Materials Inc. (US) 2008-07-02 EP claimed
WO-2007037817-A2 METHOD FOR PRODUCTION OF ISOCYANATOSILANES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-04-05 WO claimed
US-20060276644-A1 Process for the production of isocyanatosilane and silylisocyanurate GENERAL ELECTRIC COMPANY 2006-12-07 US claimed
US-7060849-B1 Method for production of isocyanatosilanes GENERAL ELECTRIC COMPANY (US) 2006-06-13 US claimed
EP-1937697-B1 METHOD FOR PRODUCTION OF ISOCYANATOSILANES MOMENTIVE PERFORMANCE MAT INC (US) 2013-10-16 EP disclosed
EP-1937697-A2 METHOD FOR PRODUCTION OF ISOCYANATOSILANES Momentive Performance Materials Inc. (US) 2008-07-02 EP disclosed
WO-2007037817-A2 METHOD FOR PRODUCTION OF ISOCYANATOSILANES MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2007-04-05 WO disclosed
US-7060849-B1 Method for production of isocyanatosilanes GENERAL ELECTRIC COMPANY (US) 2006-06-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060276644-A1 Process for the production of isocyanatosilane and silylisocyanurate SI, TST, PCMT1 MIF 640/4885GABRA1 3422/4885GABRB2 3506/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.