SCHEMBL330826

SCHEMBL330826

CCC(N=C=O)c1ccccc1C(CC)N=C=O

nearest known ligand 0.44

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MIF P14174 2/20 0.44
TSHR P16473 1/20 0.36
GABRA1 P14867 1/20 0.35
GABRB2 P47870 1/20 0.35
NOS3 P29474 1/20 0.34
NOS2 P35228 1/20 0.34
PTPRC P08575 1/20 0.31
CDC25B P30305 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5607730 0.87 MIF (0.39) MIFTSHRGABRA1GABRB2NOS3
SCHEMBL11431709 0.84 CYP2C9 (0.42) MIF
SCHEMBL331161 0.84 MIF (0.34) MIFTSHRGABRA1GABRB2
SCHEMBL23527558 0.82 CYP3A4 (0.35) MIFTSHRGABRA1GABRB2LMNA
SCHEMBL21259588 0.82 CYP3A4 (0.35) MIFTSHRGABRA1GABRB2LMNA
SCHEMBL5325552 0.82 MIF (0.35) MIF
SCHEMBL6970517 0.82 MIF (0.67) MIFGABRA1GABRB2NOS3NOS2
SCHEMBL957752 0.82 MIF (0.67) MIFGABRA1GABRB2NOS3NOS2
SCHEMBL727626 0.82 MIF (0.67) MIFGABRA1GABRB2NOS3NOS2
SCHEMBL21259585 0.81 CES2 (0.37) MIFGABRA1GABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 662 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11267953-B2 Iso(thio)cyanate composition, and resin composition including same for optical member HOYA LENS THAILAND LTD. (TH) 2022-03-08 US claimed
US-20200123345-A1 ISO(THIO)CYANATE COMPOSITION, AND RESIN COMPOSITION INCLUDING SAME FOR OPTICAL MEMBER HOYA LENS THAILAND LTD. (TH) 2020-04-23 US claimed
US-10544283-B2 Iso(thio)cyanate composition, and resin composition including same for optical member HOYA LENS THAILAND LTD. (TH) 2020-01-28 US claimed
US-20180037722-A1 ISO(THIO)CYANATE COMPOSITION, AND RESIN COMPOSITION INCLUDING SAME FOR OPTICAL MEMBER HOYA LENS THAILAND LTD. (TH) 2018-02-08 US claimed
EP-3269749-A1 ISO(THIO)CYANATE COMPOSITION, AND RESIN COMPOSITION INCLUDING SAME FOR OPTICAL MEMBER Hoya Lens Thailand Ltd. (TH) 2018-01-17 EP claimed
EP-4748866-A1 AQUEOUS POLYURETHANE DISPERSIONS AND APPLICATIONS THEREOF Covestro Deutschland AG (DE) 2026-05-27 EP disclosed
US-12606692-B2 Spectacle lens HOYA LENS THAILAND LTD. (TH) 2026-04-21 US disclosed
US-12590232-B2 Multi-region foldable adhesive film and fabrication method therefor XINMEI FONTANA HOLDING (HONG KONG) LIMITED (CN) 2026-03-31 US disclosed
US-20260071091-A1 SELF-HEALING TRANSPARENT COATING COMPOSITION USING SUNLIGHT AND APPLICATION THEREOF KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-03-12 US disclosed
EP-3983466-B1 AQUEOUS POLYURETHANE DISPERSION COVESTRO DEUTSCHLAND AG (DE) 2026-02-18 EP disclosed
EP-3778170-B1 METHOD FOR MANUFACTURING OPTICAL MEMBER HOYA LENS THAILAND LTD (TH) 2026-01-28 EP disclosed
US-12503575-B2 Fine hollow particles comprising melamine-based resin KAGOSHIMA UNIVERSITY (JP) 2025-12-23 US disclosed
EP-0528590-A1 Mercapto compound, its preparation process, and sulfur-containing urethane resins and lenses using the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1993-02-24 EP disclosed
EP-0506315-A2 Optical urethane resins and plastic lenses comprising the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-30 EP disclosed
EP-0505150-A1 Stabilizing method of isocyanate compounds and isocyanate compositions stabilized thereby MITSUI TOATSU CHEMICALS, Inc. (JP) 1992-09-23 EP disclosed
US-5087758-A Polythiourethane monomer MITSUI TOATSU CHEMICALS, INC. (JP) 1992-02-11 US disclosed
US-4946923-A S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS, INC. (JP) 1990-08-07 US disclosed
EP-0378895-A1 A mercapto compound, a high refractive index resin and lens and a process for preparing them MITSUI TOATSU CHEMICALS, Inc. (JP) 1990-07-25 EP disclosed
EP-0329388-A2 Plastic lenses having high-refractive index and process for the preparation thereof MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed
EP-0329386-A2 S-alkyl thiocarbamate base resin, plastic lens comprising the resin, and process for making the lens MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-08-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260071091-A1 SELF-HEALING TRANSPARENT COATING COMPOSITION USING SUNLIGHT AND APPLICATION THEREOF PCNA, CUTA, COL1A1 MIF 374/4885TSHR 4154/4885GABRA1 4146/4885
US-12590232-B2 Multi-region foldable adhesive film and fabrication method therefor CDH1, SMCHD1, VCL MIF 537/4885TSHR 3097/4885GABRA1 524/4885
US-12606692-B2 Spectacle lens POT1, TCOF1, CRY1 MIF 1569/4885TSHR 329/4885GABRA1 711/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.