Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.82 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.82 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.82 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.82 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.56 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | KDM5C | P41229 | 3/20 | 0.50 |
| ▸ | PHF8 | Q9UPP1 | 3/20 | 0.50 |
| ▸ | KDM2A | Q9Y2K7 | 3/20 | 0.50 |
| ▸ | KDM6B | O15054 | 2/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL468680 | 1.00 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL295052 | 1.00 | LMNA (0.82) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL518643 | 0.96 | LMNA (0.75) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL93822 | 0.96 | LMNA (0.75) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL17077298 | 0.92 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL21219028 | 0.92 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL468678 | 0.92 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL468649 | 0.92 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL2572722 | 0.92 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 | |
| Succinic Acid SCHEMBL468630 | 0.92 | LMNA (0.69) | LMNAEGLN1ALKBH5SUCNR1SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11466142-B2 | Cellulose based composition | WOODLY OY (FI) | 2022-10-11 | — | — | US | claimed |
| JP-10317228-A | — | — | None | — | — | JP | disclosed |
| EP-4214256-B1 | LOW FREE POLYURETHANE PREPOLYMER COMPOSITION FOR REACTIVE HOT MELT ADHESIVES | LANXESS CORP (US) | 2024-09-11 | — | — | EP | disclosed |
| CN-118086247-A | Improved CALB enzyme of degradable polyester and preparation method thereof | 华南理工大学 | 2024-05-28 | — | — | CN | disclosed |
| US-20230383157-A1 | LOW FREE POLYURETHANE PREPOLYMER COMPOSITION FOR REACTIVE HOT MELT ADHESIVES | LANXESS CORPORATION (US) | 2023-11-30 | — | — | US | disclosed |
| EP-4214256-A1 | LOW FREE POLYURETHANE PREPOLYMER COMPOSITION FOR REACTIVE HOT MELT ADHESIVES | LANXESS Corporation (US) | 2023-07-26 | — | — | EP | disclosed |
| EP-3638728-B1 | CELLULOSE BASED COMPOSITION | WOODLY OY (FI) | 2023-06-07 | — | — | EP | disclosed |
| CN-116194505-A | Low free polyurethane prepolymer composition for reactive hot melt adhesives | 朗盛公司 | 2023-05-30 | — | — | CN | disclosed |
| US-11466142-B2 | Cellulose based composition | WOODLY OY (FI) | 2022-10-11 | — | — | US | disclosed |
| CN-111918914-B | Homogeneous polymer mixtures, methods relating thereto and uses thereof | 伍德利有限公司 | 2022-09-23 | — | — | CN | disclosed |
| EP-2894197-A1 | AQUEOUS DISPERSION, AND ADDITIVE FOR FRACTURING WORK | Mitsui Chemicals, Inc. (JP) | 2015-07-15 | — | — | EP | disclosed |
| US-20140073539-A1 | AQUEOUS DISPERSION AND ADDITIVES FOR FRACTURING WORK | MITSUI CHEMICALS, INC. (JP) | 2014-03-13 | — | — | US | disclosed |
| EP-2695915-A1 | BIODEGRADABLE RESIN COMPOSITION AND MOLDED ARTICLE THEREOF | Mitsui Chemicals, Inc. (JP) | 2014-02-12 | — | — | EP | disclosed |
| EP-2251368-A1 | POLYESTER RESIN, A MANUFACTURING METHOD THEREOF AND USES THEREFOR | Mitsui Chemicals, Inc. (JP) | 2010-11-17 | — | — | EP | disclosed |
| JP-H10317228-A | BIODEGRADABLE CELLULOSE ACETATE-BASED AND ITS PRODUCTION | OJI PAPER CO LTD | 1998-12-02 | — | — | JP | disclosed |
| US-5708072-A | OLIGOESTERURETHANE COPOLYMERS, ACRYLATE POLYMERS | VIANOVA RESINS AKTIENGESELLSCHAFT (AT) | 1998-01-13 | — | — | US | disclosed |
| EP-0729483-A1 | LOW FOGGING POLYESTER POLYURETHANE FOAMS | BAXENDEN CHEMICALS LTD (GB) | 1996-09-04 | — | — | EP | disclosed |
| WO-1995014050-A1 | LOW FOGGING POLYESTER POLYURETHANE FOAMS | BAXENDEN CHEMICALS LIMITED (GB) | 1995-05-26 | — | — | WO | disclosed |
| WO-1993009215-A1 | COLOR-STABILIZATION SYSTEM IN LIQUID DETERGENT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1993-05-13 | — | — | WO | disclosed |
| US-4935535-A | Noncatalytic reaction | NATIONAL SCIENCE COUNCIL (TW) | 1990-06-19 | — | — | US | disclosed |