Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.96 |
| ▸ | POLB | P06746 | 3/20 | 0.96 |
| ▸ | LMNA | P02545 | 2/20 | 0.96 |
| ▸ | GAA | P10253 | 1/20 | 0.96 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | CTSL | P07711 | 1/20 | 0.56 |
| ▸ | CTSS | P25774 | 1/20 | 0.56 |
| ▸ | CTSK | P43235 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16755954 | 1.00 | MAPT (0.96) | MAPTPOLBLMNAGAAEPHX1 | |
| SCHEMBL3477664 | 0.98 | MAPT (1.00) | MAPTPOLBLMNAGAAEPHX1 | |
| SCHEMBL29757387 | 0.95 | MAPT (0.93) | MAPTPOLBLMNAGAAEPHX1 | |
| SCHEMBL7711892 | 0.91 | MAPT (0.86) | MAPTPOLBLMNAGAAEPHX1 | |
| SCHEMBL5445415 | 0.88 | MAPT (0.81) | MAPTPOLBLMNAGAAEPHX1 | |
| SCHEMBL2708330 | 0.83 | MAPT (0.73) | MAPTPOLBLMNAGAAEPHX1 | |
| SCHEMBL4676789 | 0.83 | MAPT (0.73) | MAPTPOLBLMNAGAAEPHX1 | |
| SCHEMBL4711574 | 0.83 | MAPT (0.73) | MAPTPOLBLMNAGAAEPHX1 | |
| SCHEMBL4711576 | 0.83 | MAPT (0.73) | MAPTPOLBLMNAGAAEPHX1 | |
| Hydrochloric Acid SCHEMBL29847576 | 0.81 | MAPT (0.71) | MAPTPOLBLMNAGAAEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110313158-A1 | Two Component Recyclable Heterogeneous Catalyst, Process for Preparation Thereof and its Use for Preparation of Amines | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2011-12-22 | — | — | US | claimed |
| WO-2010097815-A2 | A TWO COMPONENT RECYCLABLE HETEROGENEOUS CATALYST, PROCESS FOR PREPARATION THEREOF AND ITS USE FOR PREPARATION OF AMINES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-09-02 | — | — | WO | claimed |
| US-20240051974-A1 | DIRECT REDUCTIVE AMINATIONS WITH MONOTRIFLUOROACETOXY BORANE-AMINES | PURDUE RESEARCH FOUNDATION (US) | 2024-02-15 | — | — | US | disclosed |
| EP-2922845-B1 | ANTHELMINTIC COMPOUNDS AND COMPOSITIONS AND METHOD OF USING THEREOF | MERIAL INC (US) | 2018-06-20 | — | — | EP | disclosed |
| WO-2014096732-A1 | METAL NANO-CATALYSTS IN GLYCEROL AND APPLICATIONS IN ORGANIC SYNTHESIS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2014-06-26 | — | — | WO | disclosed |
| US-20110313158-A1 | Two Component Recyclable Heterogeneous Catalyst, Process for Preparation Thereof and its Use for Preparation of Amines | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2011-12-22 | — | — | US | disclosed |
| WO-2010097815-A2 | A TWO COMPONENT RECYCLABLE HETEROGENEOUS CATALYST, PROCESS FOR PREPARATION THEREOF AND ITS USE FOR PREPARATION OF AMINES | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2010-09-02 | — | — | WO | disclosed |
| EP-1076649-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 2001-02-21 | — | — | EP | disclosed |
| CN-1059668-C | Process for preparing N-aliphatic substituted P-phenylenediamines | MONSANTO CO (US) | 2000-12-20 | — | — | CN | disclosed |
| EP-0701992-B1 | Method of preparation of nitro substituted arylamines | BAYER AG (DE) | 1999-11-17 | — | — | EP | disclosed |
| WO-1999055679-A1 | ISOQUINOLINE COMPOUND MELANOCORTIN RECEPTOR LIGANDS AND METHODS OF USING SAME | TREGA BIOSCIENCES, INC. (US) | 1999-11-04 | — | — | WO | disclosed |
| US-5612483-A | AMINATION | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-18 | — | — | US | disclosed |
| EP-0641308-B1 | PROCESS FOR PREPARING N-ALIPHATIC SUBSTITUTED P-PHENYLENEDIAMINES | MONSANTO CO (US) | 1997-03-12 | — | — | EP | disclosed |
| EP-0701992-A1 | Method of preparation of nitro substituted arylamines | BAYER AG (DE) | 1996-03-20 | — | — | EP | disclosed |
| EP-0641308-A1 | PROCESS FOR PREPARING N-ALIPHATIC SUBSTITUTED P-PHENYLENEDIAMINES. | MONSANTO CO (US) | 1995-03-08 | — | — | EP | disclosed |
| CN-1098401-A | The preparation method of the Ursol D that N-aliphatic series replaces | MONSANTO CO (US) | 1995-02-08 | — | — | CN | disclosed |
| WO-1993024443-A1 | PROCESS FOR PREPARING N-ALIPHATIC SUBSTITUTED P-PHENYLENEDIAMINES | MONSANTO COMPANY (US) | 1993-12-09 | — | — | WO | disclosed |
| US-5252737-A | Process for preparing N-aliphatic substituted p-phenylenediamines | MONSANTO COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110313158-A1 | Two Component Recyclable Heterogeneous Catalyst, Process for Preparation Thereof and its Use for Preparation of Amines | HCN2, RAC2, HCN1 | MAPT 3456/4885POLB 2428/4885LMNA 2308/4885 |
| US-20240051974-A1 | DIRECT REDUCTIVE AMINATIONS WITH MONOTRIFLUOROACETOXY BORANE-AMINES | MAOB, BCAT2, AADAT | MAPT 2339/4885POLB 80/4885LMNA 932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.