SCHEMBL3477804

SCHEMBL3477804

O=C1c2ccc(F)cc2C(=O)N1c1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 4/20 0.64
AR P10275 2/20 0.54
ESR2 Q92731 2/20 0.49
NR1H3 Q13133 1/20 0.47
CA12 O43570 2/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CA9 Q16790 1/20 0.47
SCN2A Q99250 1/20 0.47
KMT2A Q03164 3/20 0.47
MEN1 O00255 2/20 0.47
ALDH1A1 P00352 2/20 0.47
POLB P06746 1/20 0.47
CTDSP1 Q9GZU7 1/20 0.47
GFER P55789 1/20 0.47
HSPA1A P0DMV8 1/20 0.46
PABPC1 P11940 1/20 0.46
CA7 P43166 1/20 0.46
KDM4E B2RXH2 1/20 0.45
USP2 O75604 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1734116 0.90 ESR1 (0.58) ESR1ARESR2CA12CA1
SCHEMBL1735146 0.89 ESR1 (0.57) ESR1ARESR2NR1H3SCN2A
SCHEMBL13265371 0.84 ALDH1A1 (0.65) ESR1ARESR2CA12CA1
SCHEMBL7564128 0.83 AR (0.51) ESR1ARESR2KMT2AMEN1
SCHEMBL17326723 0.83 KDM4E (0.57) ESR1ARKMT2AMEN1ALDH1A1
SCHEMBL28086894 0.82 ESR1 (0.59) ESR1ESR2NR1H3CA12CA1
SCHEMBL29710393 0.82 ESR1 (0.59) ESR1ESR2NR1H3CA12CA1
SCHEMBL17326671 0.82 MEN1 (0.62) ESR1ARESR2CA12CA1
SCHEMBL7360727 0.82 ESR1 (0.77) ESR1ESR2NR1H3KMT2AMEN1
SCHEMBL17326263 0.82 MAPK1 (0.59) ESR1ARCA12CA1CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2233512-B1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF NINGBO INST MATERIALS TECHNOLOGY & ENG CAS (CN) 2013-03-20 EP claimed
US-20110065891-A1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF CHANGCHUN HIPOLYKING CO.,LTD. (CN) 2011-03-17 US claimed
EP-2233512-A1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF Ningbo Institute Of Materials Technology And Engineering, Chinese Academy Of Sciences (CN) 2010-09-29 EP claimed
CN-105985521-B A kind of polybenzimidazoles acid imide and preparation method thereof 中国科学院宁波材料技术与工程研究所 2018-11-09 CN disclosed
CN-104311825-B Phenolphthalein type copolyimide and preparation method thereof 中国科学院宁波材料技术与工程研究所 2017-05-17 CN disclosed
CN-105985521-A Polybenzimidazole imide and preparation method thereof 中国科学院宁波材料技术与工程研究所 2016-10-05 CN disclosed
CN-104130409-B A kind of preparation method of phenolphthalein type polyimides 中国科学院宁波材料技术与工程研究所 2016-08-17 CN disclosed
WO-2015185785-A1 DERIVATIVES OF ISOINDOLIN-1,3-DIONE CONSEJO SUPERIOR DE INVESTIGACIONES CIENTÍFICAS (CSIC) (ES) 2015-12-10 WO disclosed
EP-2233512-B1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF NINGBO INST MATERIALS TECHNOLOGY & ENG CAS (CN) 2013-03-20 EP disclosed
US-20110065891-A1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF CHANGCHUN HIPOLYKING CO.,LTD. (CN) 2011-03-17 US disclosed
EP-2233512-A1 POLYTHIOETHERIMIDES AND METHOD FOR PRODUCING THEREOF Ningbo Institute Of Materials Technology And Engineering, Chinese Academy Of Sciences (CN) 2010-09-29 EP disclosed
US-7605222-B2 Gel permeation chromatography; isomeric bis(phthalimide) and bisphenol-a structural units SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2009-10-20 US disclosed
US-20070043203-A1 Gel permeation chromatography; isomeric bis(phthalimide) and bisphenol-a structural units GENERAL ELECTRIC COMPANY (US) 2007-02-22 US disclosed
US-5856421-A HEAT RESISTANCE GENERAL ELECTRIC COMPANY (US) 1999-01-05 US disclosed
US-5830974-A USING PHASE TRANSFER CATALYST GENERAL ELECTRIC COMPANY (US) 1998-11-03 US disclosed
US-5514813-A AND ALKALI METAL PHENOLATE, HIGH DILUTION, PHASE TRANSFER CATALYST GENERAL ELECTRIC COMPANY (US) 1996-05-07 US disclosed
US-4960903-A Aromatic compounds having sulfonyl groups TOA NENRYO KOGYO KABUSHIKI KAISHA (JP) 1990-10-02 US disclosed
EP-0233409-B1 AROMATIC SULFONYL COMPOUNDS Tonen Corporation (JP) 1990-09-26 EP disclosed
EP-0233409-A2 Aromatic sulfonyl compounds Tonen Corporation (JP) 1987-08-26 EP disclosed
US-3992407-A Preparation of aromatic bisimides GENERAL ELECTRIC COMPANY (US) 1976-11-16 US disclosed