Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 15/20 | 0.55 |
| ▸ | KIF11 | P52732 | 3/20 | 0.52 |
| ▸ | GABRP | O00591 | 1/20 | 0.50 |
| ▸ | GABRD | O14764 | 1/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.50 |
| ▸ | GABRE | P78334 | 1/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.50 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29733506 | 0.88 | KIF11 (0.63) | PARP14KIF11GABRPGABRDGABRA1 | |
| SCHEMBL208113 | 0.88 | KIF11 (0.63) | PARP14KIF11GABRPGABRDGABRA1 | |
| SCHEMBL30521516 | 0.86 | KIF11 (0.61) | PARP14KIF11GABRPGABRDGABRA1 | |
| SCHEMBL51674 | 0.86 | KIF11 (0.61) | PARP14KIF11GABRPGABRDGABRA1 | |
| SCHEMBL191654 | 0.86 | KIF11 (0.61) | PARP14KIF11GABRPGABRDGABRA1 | |
| Lithium SCHEMBL31282245 | 0.84 | KIF11 (0.59) | PARP14KIF11GABRPGABRDGABRA1 | |
| SCHEMBL329556 | 0.84 | KIF11 (0.59) | PARP14KIF11GABRPGABRDGABRA1 | |
| SCHEMBL38651273 | 0.81 | KIF11 (0.55) | PARP14KIF11GABRPGABRDGABRA1 | |
| SCHEMBL5810425 | 0.79 | KIF11 (0.75) | PARP14KIF11GABRPGABRDGABRA1 | |
| SCHEMBL147411 | 0.79 | BCHE (0.64) | PARP14KIF11GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2448925-B1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORP (JP) | 2017-12-06 | — | — | EP | claimed |
| US-8927121-B2 | Emissive aryl-heteroaryl compounds | NITTO DENKO CORPORATION (JP) | 2015-01-06 | — | — | US | claimed |
| US-8771845-B2 | — | — | 2014-07-08 | — | — | US | claimed |
| US-20130284907-A1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2013-10-31 | — | — | US | claimed |
| EP-2448925-A1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | Nitto Denko Corporation (JP) | 2012-05-09 | — | — | EP | claimed |
| WO-2011008560-A1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2011-01-20 | — | — | WO | claimed |
| US-20100326526-A1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2010-12-30 | — | — | US | claimed |
| EP-2448925-B1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORP (JP) | 2017-12-06 | — | — | EP | disclosed |
| US-8927121-B2 | Emissive aryl-heteroaryl compounds | NITTO DENKO CORPORATION (JP) | 2015-01-06 | — | — | US | disclosed |
| US-8771845-B2 | — | — | 2014-07-08 | — | — | US | disclosed |
| US-20130284907-A1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2013-10-31 | — | — | US | disclosed |
| US-8354668-B2 | Emissive triaryls | NITTO DENKO CORPORATION (JP) | 2013-01-15 | — | — | US | disclosed |
| EP-2448925-A1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | Nitto Denko Corporation (JP) | 2012-05-09 | — | — | EP | disclosed |
| US-20120015998-A1 | PHOTOTHERAPY METHODS AND DEVICES COMPRISING EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2012-01-19 | — | — | US | disclosed |
| WO-2012009283-A1 | PHOTOTHERAPY METHODS AND DEVICES COMPRISING EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2012-01-19 | — | — | WO | disclosed |
| WO-2011008560-A1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2011-01-20 | — | — | WO | disclosed |
| US-20100326526-A1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | NITTO DENKO CORPORATION (JP) | 2010-12-30 | — | — | US | disclosed |
| US-20100327269-A1 | EMISSIVE TRIARYLS | NITTO DENKO CORPORATION (JP) | 2010-12-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120015998-A1 | PHOTOTHERAPY METHODS AND DEVICES COMPRISING EMISSIVE ARYL-HETEROARYL COMPOUNDS | ARNT, AHR, AR | PARP14 278/4885KIF11 3262/4885GABRP 4263/4885 |
| US-20100327269-A1 | EMISSIVE TRIARYLS | CRY1, TYR, CRY2 | PARP14 768/4885KIF11 2494/4885GABRP 4608/4885 |
| US-20100326526-A1 | EMISSIVE ARYL-HETEROARYL COMPOUNDS | AHR, AR, ARNT | PARP14 217/4885KIF11 3784/4885GABRP 3777/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.